Inhibition of Neurosteroid Synthesis Increases Asphyxia-Induced Brain Injury in the Late Gestation Fetal Sheep

April 2007 in “ Neuroscience ”

Tamara Yawno, Edwin B. Yan, David W. Walker, Jonathan J. Hirst

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Research cited in this study

4 / 4 results

research Finasteride Inhibits the Progesterone-Induced Spike-Wave Discharges in a Genetic Model of Absence Epilepsy

23 citations , July 2003 in “Pharmacology, Biochemistry and Behavior”

Finasteride blocks progesterone's effect on absence seizures in rats.

research Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABA A Receptor Function and Seizure Susceptibility

269 citations , May 2002 in “Journal of Neuroscience”

Stress increases neurosteroids that help prevent seizures.

research Effect of Finasteride on Behavioral Arousal and Somatosensory Evoked Potentials in Fetal Sheep

36 citations , June 2001 in “Neuroscience Letters”

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

research Finasteride, a 5alpha-Reductase Inhibitor, Blocks the Anticonvulsant Activity of Progesterone in Mice

48 citations , February 1999 in “PubMed”

Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.

Related Research

1 / 1 results

research Finasteride Inhibits the Progesterone-Induced Spike-Wave Discharges in a Genetic Model of Absence Epilepsy

23 citations , July 2003 in “Pharmacology, Biochemistry and Behavior”

Finasteride blocks progesterone's effect on absence seizures in rats.