Effects of Huoxue Bushen Mixture on Vascular Endothelial Growth Factor Expression in Human Dermal Papilla Cells
January 2010
in “
Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai
”
New to Vascular Endothelial Growth Factor? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that Huoxue Bushen Mixture increased VEGF expression and the proliferation of dermal papilla cells, suggesting it may promote hair growth compared to control treatments in rats. Our plain-language summary of this paper — not a Tressless recommendation.
The study investigated the effects of Huoxue Bushen Mixture on the proliferation of dermal papilla cells and the expression of vascular endothelial growth factor (VEGF) in these cells. Using 12 SD rats divided into three groups, the researchers compared the effects of Huoxue Bushen Mixture, Yangxue Shengfa Capsule, and sodium chloride. Results showed that the Huoxue Bushen Mixture group had a higher number of dermal papilla cells and significantly increased VEGF mRNA and protein expression compared to the other groups. The study concluded that Huoxue Bushen Mixture could up-regulate VEGF expression in human dermal papilla cells, thereby increasing cell proliferation and promoting hair growth.