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Physician responses are better than ChatGPT for dermatology questions.

This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.

In this case report, a three-generation family with Gorlin-Goltz syndrome showed a heterozygous PTCH1 splice-donor variant associated with the disease, and two affected relatives benefited from individualized, side-effect-guided dosing of the drug sonidegib, experiencing regression of basal cell carcinoma lesions.

This study found PRP treatment significantly increased hair count and anagen hairs in male patients with androgenetic alopecia, but there was no correlation between therapeutic response and platelet or growth factor levels.

This article introduces a new column focusing on global hair societies, following the ethos of the Global Council of Hair Restoration Surgery, but presents no new research findings.

The researchers reported that disrupting the RPGRIP1L gene in mice impaired desmosome function, causing skin blistering, and their findings suggest that PKCβII inhibition could help treat pemphigus.

In this study, Korean Red Ginseng showed protective effects against chemotherapy-induced premature hair follicle aging in an in vitro model by modulating specific cellular protein expressions.

This study found that glibenclamide exhibited a cytostatic effect on MDA-MB-231 breast cancer cells, potentially mediated through K ATP channels, and enhanced the antiproliferative impact of doxorubicin.

This study found that the scalp coverage scoring (SCS) method is a non-invasive and reproducible technique that effectively measures hair growth and loss dynamics in male subjects with androgenetic alopecia.

This report announces that the International Society of Hair Restoration Surgery received Accreditation with Commendation.

This study found that injecting growth factor concentrates into the scalp of five patients with androgenic alopecia led to notable improvements in hair density and quality over eight weeks, with patients reporting satisfaction and minimal side effects.

This announcement explains the Fellow designation for hair restoration surgeons meeting specific educational criteria, without reporting new research findings.

This obituary honors Dr. Grant Koher, a respected member of the ISHRS and a diplomate of the American Board of Hair Restoration Surgery, and reports no new research findings.

In a dermal Gorab knockout mouse model, this study found that Gorab mutations increase P53 protein accumulation and disrupt extracellular matrix expression, contributing to accelerated skin aging and suggesting a pathway involving epigenetic regulation.

Few dermatology programs mention gender-affirming care, highlighting a need for better training and visibility.

This pilot study found that growth factor concentrate therapy improved hair growth in patients with androgenetic alopecia, was well tolerated, and achieved high patient satisfaction.

This report describes a rare case of Graham-Little–Piccardi–Lassueur syndrome in a 46-year-old male, highlighting its typical features such as scarring alopecia and lichenoid follicular eruptions.

This study found that resveratrol promoted hair growth in mice and human hair follicles, suggesting its potential as a treatment for hair loss.

This study found that a 22-bp InDel polymorphism in the FGF7 gene was significantly associated with growth traits in goats, with genotypes ID and/or II linked to better growth compared to genotype DD, indicating its potential as a molecular marker in breeding programs.

In this animal study, ginsenoside Rb1 demonstrated therapeutic effects on hypertrophic scar remodeling, with the highest efficacy observed at a dose of 0.56 mg.

This review discusses Hutchinson-Gilford progeria syndrome, highlighting its phenotype, pathogenesis, and its potential insights into natural aging and cardiovascular diseases, but it reports no new research findings.

This meeting announcement reports no new research results; it describes the upcoming Annual Meeting of the International Society of Hair Restoration Surgery in 2001.

This review discusses gender identity disorder in Japan, highlighting the high prevalence and challenges in accessing appropriate treatment, and calls for wider understanding among medical professionals.

In this study, researchers reported that both PRP and L-GF injections are effective in enhancing hair density and reducing recovery time post-transplantation in men with androgenetic alopecia, with L-GF showing slightly better but statistically insignificant results.

This review summarizes evidence and adverse event management recommendations for Sacituzumab Govitecan in metastatic triple-negative breast cancer and hormone receptor-positive breast cancer, emphasizing favorable survival data from clinical trials.

This review explores existing research on the therapeutic benefits of ginseng and ginsenosides for various dermatological conditions, but it reports no new clinical results.

In this study, researchers found that during late pregnancy, neuroactive steroid fluctuations increase the number of extrasynaptic GABAA receptors in rat hippocampal cells.

This pilot study suggests that a new preparation of platelet-rich plasma gel may improve symptoms and tissue regeneration in patients with en coup de sabre scleroderma, though further trials are needed to clarify its role.

This study found that a single injection of Platelet Rich Stroma improved knee function and reduced pain and stiffness in patients with knee osteoarthritis over twelve months.

This paper proposes that GDNF signaling may enhance skin regeneration and hair follicle formation by influencing dermal fibroblast differentiation, particularly following injury.