research Chemotherapy-Induced Alopecia
Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.
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research Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and Anti-Hair Loss Effects
Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.
research The Harmonies Played by TGF-β in Stem Cell Biology
TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Androgens and Hair Growth
Androgens can both increase and decrease hair growth in different parts of the body.
research Complex Hair Cycle Domain Patterns and Regenerative Hair Waves in Living Rodents
Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.
research Involvement of DKK1 Secreted From Adipose-Derived Stem Cells in Alopecia Areata
A protein from fat-derived stem cells, DKK1, is linked to hair loss and blocking it may help treat alopecia areata.
research Alterations in Hair Follicle Dynamics in Women
Hormonal changes after childbirth and menopause can lead to women's hair loss and facial hair growth, with a need for better treatments.
research 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA)
3D cell cultures are better for testing hair growth treatments than 2D cultures.
research Single-Cell Transcriptomics Reveals Lineage Trajectory of Human Scalp Hair Follicle and Informs Mechanisms of Hair Graying
The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
research A Study on the Extracts of Cuscuta Reflexa Roxb. in the Treatment of Cyclophosphamide-Induced Alopecia
Cuscuta reflexa extracts helped regrow hair in rats with drug-induced hair loss.
research Effect of Adiantum Capillus-Veneris Linn on an Animal Model of Testosterone-Induced Hair Loss
Adiantum capillus-veneris Linn reduced hair loss and improved hair growth in mice with testosterone-induced alopecia.
research Comparative Hair Restorer Efficacy of Medicinal Herb on Nude (Foxn1nu) Mice
Eclipta alba extract was found to be effective in promoting hair growth in hairless mice.
research Effective Medical Treatment for Common Baldness in Women
Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.
research A Rare Complication From Prostaglandin Analogue Therapy
Prostaglandin eye drops for glaucoma can rarely cause too much cheek hair growth.
research Discovery of Hair-Follicle-Associated Pluripotent Stem Cells
HAP stem cells in hair follicles could help repair nerves and spinal cords.
research Imaging Tumor Angiogenesis With Fluorescent Proteins
Fluorescent proteins help visualize and understand tumor blood vessel growth.
research Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep
Editing the FGF5 gene in sheep increases fine wool growth.
research Managing Cutaneous Manifestations of Hyperandrogenic Disorders
Birth control pills help treat skin and hair growth problems linked to high male hormone levels.
research Vitamin D and the Skin: Physiology and Pathophysiology
Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
research Nanostructured Lipid Carriers Loaded with Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia
A new treatment for hair loss uses tiny lipid carriers to deliver a mix of minoxidil and latanoprost directly to hair follicles, promoting hair growth and being well tolerated by the skin.
research Hair Coloration by Gene Regulation: Fact or Fiction?
Gene regulation could revolutionize hair color by altering pigmentation from within.
research The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle
The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
research EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner
EGFR helps control how hair grows and forms without needing p53 protein.
research Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth
Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
research Finasteride
Finasteride effectively treats baldness but may cause sexual side effects.
research The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target During Hair Follicle and Nail Differentiation
HOXC13 is essential for hair and nail development by regulating Foxn1.
research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Wnt signaling is crucial for skin development and hair growth.
research Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus
Melatonin can increase cashmere yield by altering gene expression and restarting the growth cycle early.