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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

The Rotterdam Study aims to understand various diseases in older adults.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Some medicinal plants can help heal wounds and may lead to new treatments.