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Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Flutamide rarely causes liver toxicity in prostate cancer patients.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Nerves and chemicals in the body can affect hair growth and loss.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.