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Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

This study observed specific expression patterns of three zebrafish estrogen receptor genes during development, highlighting robust co-expression of esr2a and esr2b in primary neuromasts, branchial arches, and other tissues.

This review discusses the hormonal and genetic factors influencing acne development, emphasizing the role of androgens and insulin signaling but reports no new clinical results.

This study found that the enzyme A20 helps regulate EDAR-induced NF-κB signaling in mice, preventing ectodermal abnormalities like disheveled hair and assuring proper skin and appendage development.

This article reviews the hormonal and medication-related factors associated with acne development but does not present new research findings.

In this study, key histologic features such as mucinous perifollicular fibroplasia were identified to aid in the diagnosis of lichen planopilaris.

In this study, EDA-A2 transgenic mice exhibited multifocal myodegeneration dependent on XEDAR, suggesting a potential role for XEDAR in skeletal muscle homeostasis.

This review explores how androgens and growth hormone influence the development of terminal hairs and sebaceous glands, attributing variability in hirsutism and acne to differing genetic sensitivities to androgens, but reports no new experimental data.

This study found that sebocytes in human skin express and secrete certain adipokines, suggesting they might play active roles in skin inflammation rather than just being targets.

This review discusses various theories of the causes and management strategies for hidradenitis suppurativa, reporting no new experimental results, with a focus on the immune basis of the disease.

In this study, researchers found that disrupting the PRL gene in mice led to earlier hair molting, especially in females, suggesting that PRL inhibits murine hair cycle events.

This paper provides evidence supporting the formation of new hair follicles in adult humans, building on findings previously demonstrated in rabbits.

This article reviews current strategies and advancements in regenerating skin appendages and sensory nerves in tissue-engineered skin, highlighting the challenge of restoring skin sensations like pain, temperature, and touch to improve patients’ quality of life.

This review discusses the chronic nature of acne and its association with various systemic diseases, but reports no new clinical findings, highlighting the need for further study on its nutritional or genetic links.

This review discusses the role of Edar signaling in hair follicle development and cycling, emphasizing its impact on cell fate, differentiation, and interactions with other pathways, but reports no new results.

This study demonstrates that PAD1 and PAD3 are involved in hair follicle differentiation, while PAD1 and PAD2 may play a role in the physiology of sweat glands and arrector pili muscles.

This study found that inhibiting AP-1 activity in mice modified tumor development, leading to transdifferentiation between squamous and sebaceous tumors, with molecular analysis suggesting AP-1's role in maintaining tumor cell identity.

This review discusses the advancements and challenges in developing in vitro human skin models incorporating components like vasculature for drug testing and disease research, but reports no new clinical results.

This article discusses the structure and function of the skin and its role in skin disease pathophysiology and reports no new research findings.

This study found HLA and beta 2-microglobulin antigens in various skin structures, with specific localization patterns in keratinocytes and hair follicle components, but not in eccrine or apocrine glands.

This study found that the pituitary gland is crucial for normal pelage color cycles in weasels, with certain hormones influencing regrowth of pigmented or white hair after molting.

This study found that overexpressing the BMP inhibitor Noggin in transgenic mice led to a significant loss of nontylotrich hair follicles, suggesting a critical role for BMP signaling in hair follicle morphogenesis and cycling.

Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.

This review explores the role of FGFR2b-signaling in the pathogenesis of acne, highlighting its influence on sebaceous gland physiology and the effects of anti-acne agents like isotretinoin.

This study found that keratin K17 is induced in the suprabasal layer of psoriatic scalp epidermis during epidermal hyperproliferation, suggesting it is not specific to hair follicles.

This study reported that using condensed nanofat combined with fat grafts significantly improved the aesthetic and functional aspects of atrophic facial scars in 20 patients, as assessed by both patients and plastic surgeons using the Patient and Observer Scar Assessment Scale.

This review examines the location and markers of hair follicle stem cells, finding that they are primarily located in the bulge region and can contribute to various skin structures, but challenges remain in distinguishing them from their progeny.

This study used an autoradiographic technique to observe that germicides in surfactants are primarily deposited on the stratum corneum of guinea-pig and human skin.

This study found that sex steroid hormone receptors are largely maintained during the transformation of skin appendages to neoplasms, except for androgen and estrogen receptors in sweat and sebaceous gland tumors.

This study identified that the enzyme CYP2B12 is skin-specific and likely plays a role in the metabolism of arachidonic acid, a key component in lipid signaling within sebaceous glands.