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This study found that probiotics, specifically the L. plantarum MTCC 1325 strain, may have protective effects against Alzheimer's-like symptoms induced by D-Galactose in animal models, suggesting potential therapeutic use for neurodegenerative disorders.

This case report suggests that intracanal medication with calcium hydroxide paste may alleviate colitis symptoms triggered by Formacresol used during dental retreatment in a 46-year-old patient.

This study suggests that among GLP-1 agonists, liraglutide and exenatide are linked to the highest rates of gastrointestinal issues, including potentially pancreatitis-related enzyme changes noted in animal models.

In this study, a novel CT@GA-gel hybrid hydrogel was developed for diabetic wound treatment, demonstrating improved mechanical properties, tissue adhesion, and chronic wound healing benefits, including immune regulation and re-epithelialization, due to enhanced crosslinking and ROS scavenging by incorporated carbon dots.

This review discusses how functionalized hydrogels can modulate the microbiome to aid tissue regeneration and infection control, highlighting their potential to deliver therapeutic agents effectively and support beneficial immune responses.

This study found that sterile fucoidan promotes T cell proliferation but reduces differentiation at higher concentrations and suppresses osteogenic differentiation in co-cultured environments.

This study reported that a colistin sulfate-loaded nanoemulgel showed improved antimicrobial activity and skin permeability compared to a CS solution, suggesting a potential new approach for treating severe infections caused by multidrug-resistant bacteria.

This case report discusses the intertwined nature of eating disorders and gender dysphoria in a patient, suggesting that ED symptoms in individuals with GD might act as a strategy to cope with biological sex traits.

Combination antibiotic therapy is more effective but causes more side effects.

This study found that nanobubble-encapsulated diclofenac with ultrasound-targeted microbubble destruction (DNBs-UTMD) can enhance the anti-tumor efficacy of Doxil® by regulating the tumor immune microenvironment, improving drug uptake, and increasing T cell responses while reducing immune-suppressive cells in the process.

This study identified a novel mutation in the EDA gene, which may impair protein stabilization and be involved in the development of oligodontia and mild ectodermal dysplasia phenotypes.

In this study, the authors observed that controlled microflora in gnotobionts leads to delayed maturation of T-dependent lymphocytes in the thymus, affecting cellular immunity reactions.

This study found that GD-23, a dipeptide ligand of TSPO, exhibited an anxiolytic effect in the elevated plus maze test, which was inhibited by selective neurosteroid synthesis inhibitors, suggesting a neurosteroidogenic mechanism.

This case study reports that bisphosphonate therapy, used to treat osteoporosis, can lead to jawbone necrosis, as demonstrated in an 82-year-old patient who experienced severe complications requiring surgical intervention. The authors recommend comprehensive dental care before and avoidance of invasive procedures during bisphosphonate treatment.

In this study, a novel geometric medicine approach, utilizing the N-K Universal Computer, was reported to eliminate aflatoxin contamination and significantly reduce cancer rates across the "Aflatoxin Belt" through precision targeting of harmful fungi while preserving ecological balance, without observed toxicity or resistance.

This study found that TCDD significantly reduced EGF receptor binding in various animal models, linked to toxic symptoms like weight loss and developmental delays, with receptor phosphorylation persisting several days.

This abstract lists numerous dermatological side effects and reactions associated with various medications but reports no new research findings.

This study found that cepharanthine can inhibit gastric cancer cell activity by inducing oxidative stress and altering energy metabolism, suggesting its potential for gastric cancer treatment.

In this case report, a three-generation family with Gorlin-Goltz syndrome showed a heterozygous PTCH1 splice-donor variant associated with the disease, and two affected relatives benefited from individualized, side-effect-guided dosing of the drug sonidegib, experiencing regression of basal cell carcinoma lesions.

This study suggests that the anticonvulsant effects of deoxycorticosterone in young rats may be mediated by its metabolites and interactions with multiple receptors, including mineralocorticoid and progesterone receptors.

This case report identifies collagenous gastritis as the cause of chronic gastrointestinal symptoms in a 27-year-old male, characterized by severe chronic inactive gastritis and a distinctive subepithelial collagen band.

This review summarizes recent advances in the development of engineered polypeptide-based drug delivery systems for cancer therapy, highlighting their potential to improve treatment efficacy and reduce side effects.

This study identified specific profiles and courses of adverse events associated with boron neutron capture therapy for head and neck cancer, suggesting differences based on the beam incidence site.

This study found that ion-paired solutions significantly improved the skin penetration of risedronate in hairless mice compared to risedronate alone.

This review discusses recent advances in polydopamine-based biomaterials and their growing potential in personalized medicine, but reports no new experimental results; the authors highlight both opportunities and challenges for future applications.

This study found that among Japanese IBD patients, the NUDT15 p.Arg139Cys variant was significantly associated with thiopurine-induced leukopenia and severe hair loss, suggesting its genotyping is important for predicting these adverse events.

This article discusses the development and clinical progress of PROTAC technology, particularly focusing on the New Drug Application for vepdegestrant, an estrogen receptor-targeting PROTAC, marking significant advancements in targeted protein degradation therapies.