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People with androgenetic alopecia may have a higher genetic risk for cardiovascular diseases.

This study developed an in vitro model using NTERT keratinocytes expressing AEC-related TP63 mutations, which replicated skin defects observed in AEC patients and offers a valuable tool for understanding the disorder and developing new treatments.

This review discusses the complex genetic factors contributing to androgenetic alopecia, highlighting the variability in genetic risk across different populations and the emerging understanding of personalized treatment strategies, but reports no new clinical findings.

This study found that elevated tissue RBP4 levels correlate with disease severity in alopecia areata and decrease after effective baricitinib treatment, while the rs3758539 polymorphism is linked to disease susceptibility but not to treatment response.

This study highlights a comprehensive approach for authenticating and assessing the quality of herbal medicines using a combination of physiological, morphological, and molecular techniques, including HPTLC, ICP-MS, UV spectroscopy, and DNA barcoding, to ensure the standardization of herbal medicinal products, particularly Eclipta alba.

This review identifies 33 genetic syndromes associated with alopecia areata in children, with 67% fully genetically elucidated, and highlights their clinical features, providing insights that may aid in early prediction, diagnosis, and personalized treatments.

This study found evidence for a genetic basis of polycystic ovary syndrome, indicating an autosomal dominant pattern of inheritance among first-degree relatives.

This review discusses forensic DNA phenotyping and its potential applications, particularly for human identification in Latin American populations, but notes challenges due to genetic diversity and reports no new results.

This study examines the genetic underpinnings of chronic dermatological conditions like acne, androgenetic alopecia, and alopecia areata, concluding that a deep understanding of these mechanisms can advance patient-specific treatments and inform cosmetic practices related to skin and hair health.

In this case report, a 10-month-old ethnic minority infant from Xinjiang with acrodermatitis enteropathy improved clinically and biochemically after zinc supplementation, underscoring the importance of early genetic testing for SLC39A4 mutations and individualized zinc therapy in managing this disorder.

In this case study, a 10-month-old minority infant from Xinjiang, China, with acrodermatitis enteropathy caused by an SLC39A4 gene mutation showed clinical improvement and increased zinc levels following zinc supplementation, highlighting the importance of early genetic testing and customized treatment in managing the disorder.

In this study, researchers identified two significant genetic polymorphisms in the 3'-UTR of the HSP70 gene in Moa buffalo, which may play an important role in heat adaptation, providing insights for conservation and performance improvement in tropical climates.

In this review, researchers analyzed literature on trichotillomania and found advances in understanding its neurobiology—highlighting dysregulated reward circuits and genetics—and treatments, with behavioral therapy and innovative pharmacological approaches improving outcomes where traditional SSRIs do not.

This review highlights advances in understanding trichotillomania's neurobiology and treatment, noting behavior therapy's effectiveness and new pharmacological and digital therapies, while addressing underdiagnosis, stigma, and research gaps.

In this literature review, researchers highlighted that trichotillomania involves dysregulated reward circuits, abnormal sensory processing, and potential genetic factors, advancing both therapeutic strategies and understanding of the condition, but stigma and provider training gaps persist in effective care provision.

This study identified the FGF5:c.578C>T variant as linked to long hair in Akitas in Japan and suggests that genetic testing could help improve their breeding practices and welfare.

This review examines the genetics of acne vulgaris, concluding that stem/progenitor cell maintenance and cellular migration are key processes in its pathogenesis, potentially shifting future treatment strategies beyond traditional antibiotics and retinoids, which have notable side effects.

This study found that integrating breed-specific BOA and SNP-based models helps reveal the genetic factors involved in thermotolerance traits in beef cattle, enhancing insights into thermoregulation and potentially improving cattle's heat resilience.

This study identified three genetic loci influencing hair density in East Asian populations and found associations with demographic and lifestyle factors like age, sex, and BMI. The results also suggest possible genotype-specific responses to finasteride for managing hair disorders.

This study found that genetic predictions of male pattern baldness from European populations do not generalize well to African populations, highlighting significant differences in genetic architecture between them.

This study found that cataracts, hair changes, short stature, and low bodyweight are key indicators for diagnosing Werner syndrome in patients under 30, differing from older age group symptoms.

In this study, researchers found that specific genetic variations at loci rs1160312, rs6113491, and rs1041668 are independent risk factors for androgenetic alopecia in men, and these risks can be influenced by diet.

This study utilized polarized light microscopy to examine hair shafts in ten children with rare genetic disorders, such as Netherton syndrome and ectodermal dysplasia, providing valuable diagnostic insights into hair thickness, composition, and structural irregularities associated with these conditions.

This study examined Prunus mira populations in the Qinghai-Tibetan Plateau and found high genetic diversity and substantial phylogeographic structure, suggesting geographic isolation limits gene flow; the researchers propose conservation strategies to preserve genetic resources.

This source reports that PCOS, a complex endocrinal condition, is characterized by hyperandrogenism, which leads to symptoms like hirsutism, acne, and alopecia; genetic factors and hypothalamic-pituitary-ovarian axis disruption play significant roles in its development, but more research is needed to understand these mechanisms fully.

Genetic factors affecting skin health and body weight may increase the risk of dermatophytosis.

Genetic defects in the Wnt/PCP pathway may cause congenital yellow nail syndrome.

This case report details an extremely low-birth-weight preterm neonate presenting with unique dermatologic symptoms, leading to a diagnosis of neonatal inflammatory skin and bowel disease due to a novel homozygous EGFR gene mutation, highlighting the importance of genetic testing in ambiguous cases.

Certain genetic variants and pathways are linked to hair loss.

In this study, researchers identified three novel genetic loci associated with androgenetic alopecia, including one with significant association in females only, which may indicate a role for sex-specific genetic factors in patterned hair loss.