The Role of Rs6152 Allele and Non-Genetic Factors in Androgenetic Alopecia: A Pilot Study in the Indonesian Local Population

This pilot study investigated the role of the rs6152 allele and non-genetic factors in androgenetic alopecia (AGA) in the Indonesian local population. The study involved 100 participants, both with and without alopecia. The results showed that the rs6152 allele was not a reliable genetic marker for AGA in this population, as only 2% of individuals had the non-risk alleles and there was no significant association between the allele and AGA. However, a strong association was found between family history and AGA risks, suggesting an autosomal dominant inheritance pattern with sex limitation. Non-genetic factors such as age, gender, hypertension status, and BMI were also significantly associated with AGA risk. This indicates that AGA in the Indonesian local population is a complex condition with multifactorial causes.