No Genetic Support for a Contribution of Prostaglandins to the Etiology of Androgenetic Alopecia

July 2013 in “ Faculty of Health; Institute of Health and Biomedical Innovation ”

Stefanie Heilmann, Dale R. Nyholt, Felix F. Brockschmidt, Axel M. Hillmer, Christoph Herold, C. Maan, Thomas Becker, Nicholas G. Martin, Markus M. Nöthen, Lambertus A. Kiemeney, Sita H. Vermeulen

androgenetic alopecia AGA genetic predisposition androgens genome-wide association studies GWAS genetic loci candidate genes biological pathways

TLDR Prostaglandins don't genetically contribute to hair loss.

The document discussed the genetic factors contributing to androgenetic alopecia (AGA), a common condition characterized by hair loss. It highlighted that while genetic predisposition and androgens are known factors, a significant portion of the genetic contribution to AGA remained unidentified. The study suggested using genome-wide association studies (GWAS) combined with knowledge of specific biological factors to identify additional genetic loci. This approach could help pinpoint candidate genes and biological pathways important in AGA development. However, the document concluded that there was no genetic support for prostaglandins contributing to the aetiology of AGA.

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