26 citations,
July 2012 in “Journal of family planning and reproductive health care” The document says that hirsutism in women usually needs hair removal and hormone treatment to manage symptoms and improve well-being.
20 citations,
March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
14 citations,
September 2017 in “General and comparative endocrinology” Barn owls with smaller black spots have higher testosterone levels, which might be due to genetic effects on hormone regulation rather than hormone effects on coloration.
[object Object] 25 citations,
August 2006 in “Human Reproduction” Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.
3 citations,
October 2011 in “JAT. Journal of applied toxicology/Journal of applied toxicology” Doxazosin mesylate and saw palmetto cause genetic changes in fruit flies.
December 2024 in “Medical Review” Organoids help study and treat genetic diseases, offering personalized medicine and therapy testing.
44 citations,
January 1999 in “Advances in pharmacology” The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.
15 citations,
October 2011 in “Gynecological Endocrinology” Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.
14 citations,
May 2013 in “American Journal of Physiology-endocrinology and Metabolism” Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
3 citations,
February 2018 in “Human Reproduction” A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.
51 citations,
January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
20 citations,
June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
12 citations,
January 2016 in “Endocrinology, diabetes & metabolism case reports” Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.
November 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” Pig hair cortisol levels are inheritable and linked to stress responses, which could help select for more resilient pigs.
29 citations,
January 2010 in “Methods in Enzymology” The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
29 citations,
March 2021 in “Frontiers in Endocrinology” Testosterone may influence COVID-19 severity and outcomes.
4 citations,
January 2023 in “Andrology” The testes produce sperm and hormones essential for male development.
July 2023 in “Journal of Biomedical Science” Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
4 citations,
January 2011 in “Dermatology” A patient grew extra hair on their ears after treatment for testicular cancer, possibly due to hormonal changes or genetics.
May 2023 in “IntechOpen eBooks” More research is needed to understand how testosterone is maintained in adult males.
September 2022 in “Translational Andrology and Urology” Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.
22 citations,
June 2004 in “Journal of The European Academy of Dermatology and Venereology” A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.
78 citations,
August 2012 in “Human molecular genetics online/Human molecular genetics” A new gene, JMJD1C, may affect testosterone levels in men.
37 citations,
April 2013 in “Plastic and Reconstructive Surgery” Genetic and environmental factors, like smoking and exercise, affect male hair loss.
4 citations,
June 2019 in “Journal of Cosmetic Dermatology” Women with hirsutism have different levels of omentin-1, which may be linked to the condition and its genetic aspects.
January 2023 in “International Journal of Clinical and Medical Education Research” Correct testosterone levels for age to treat prostate cancer, using low dose treatments as necessary.
19 citations,
November 2021 in “Reviews in endocrine and metabolic disorders” Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.
1 citations,
January 2022 in “Food & Function” Certain Egyptian Sabal fruit extracts may help treat anti-androgenic diseases like benign prostatic hyperplasia.
1 citations,
November 1995 in “Postgraduate medical journal” A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.
[object Object] January 2024 in “Brazilian Journal of Hair Health” Testosterone therapy in transgender men can lead to hair loss, with the risk increasing over time and influenced by family history.