Androgenetic Alopecia in Transgender Men: A Literature Review and Therapeutic Insights

    January 2024 in “ Brazilian Journal of Hair Health ”
    Pedro Augusto Laurindo Igreja Marrafa, Bruno Natal, Fabiana Padovez
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    TLDR Testosterone therapy in transgender men can lead to hair loss, with the risk increasing over time and influenced by family history.
    The literature review titled "Androgenetic Alopecia in Transgender Men: A Literature Review and Therapeutic Insights" examines the side effects of hormonal treatment in transgender men, specifically focusing on hair loss, or alopecia. The research, which used an exploratory bibliographic approach and sourced materials from databases like Web of Science, Cochrane, and Medline, found that studies on transgender men undergoing testosterone therapy reveal varying percentages of Androgenetic Alopecia (AGA). The incidence of AGA appears to correlate with the duration of hormonal treatment. However, there are conflicting findings on predictive factors, such as age and the type of testosterone therapy, which complicate the understanding of AGA development. The study also found that genetic predisposition and family history influence the onset of hair loss in transgender men, with those having a family history experiencing it earlier than those without.
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