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PGD2 stops hair growth and is higher in bald men with AGA.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Current treatments for alopecia show no significant long-term benefits.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Too much androgen can cause hair loss; finasteride may help.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The definition of Polycystic Ovary Syndrome may change with new research, and careful screening is key for managing the condition.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.