This study identified genetic regions evolving at different rates in hairless mammals, suggesting that specific genomic changes may contribute to the evolution of hairlessness across various species.
December 2021 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Men can have genetic risks for PCOS-related traits like obesity and diabetes.
August 2014 in “Journal of The American Academy of Dermatology” This letter discusses a study where obesity was linked to hirsutism but not androgenetic alopecia in children and adolescents, contrasting with previous findings in adult men.
January 2012 in “Methods in pharmacology and toxicology” This review discusses the expanding understanding of TRPV3's role in pain and skin pathology, while highlighting the need for further pharmacological research to fully resolve its functions.
August 2009 in “Journal of Oral and Maxillofacial Surgery” This review discusses the concept of "Donor Dominance" in hair transplantation, initially introduced by Dr. Norman Orentreich, and reports no new clinical results.
January 2008 in “대한피부과학회지” This study found that among Korean patients with androgenetic alopecia, a significant portion had a family history, and pelvic ultrasound showed increased rates of abnormalities in female patients, although not recommended as a routine test.
December 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This review covers various dermatological studies, including findings on glycerol's optical clearing effects, approaches to keloid prevention, itch quantification, baldness heritability, and fumaric acid esters for psoriasis, without presenting new clinical results.
January 2021 in “Przegla̧d dermatologiczny” This study found that women had better knowledge and interest in androgenetic alopecia than men, especially about its definition and normal hair loss rates, but both sexes struggled with understanding its etiology and symptoms.
January 2015 in “Journal of Clinical Dermatology” In this study, family history of androgenetic alopecia was associated with earlier onset and increased severity of hair loss in men, but had no impact on treatment effectiveness.
January 2009 in “Egyptian Journal of Medical Human Genetics” This study, conducted among Egyptians, found a borderline significant association between the Stul polymorphism of the androgen receptor gene and androgenetic alopecia in males, with higher androgen receptor expression in balding scalp areas.
15 citations
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May 2003 in “Choice Reviews Online” This review discusses various misconceptions and myths in medicine-related topics, spanning body functions, aging, disease, nutrition, alternative medicine, and health risks, and provides no new experimental results.
July 2025 in “Frontiers in Animal Science” This editorial discusses the need for continued research on animal fibers, highlighting recent advances in the field and the impact of economic factors favoring meat over fiber production on research volume.
January 2015 in “Plastic and Reconstructive Surgery” This review discusses the book "Hair Transplantation: The Art of Follicular Unit Micrografting and Minigrafting" by Drs. Barrera and Uebel, which comprehensively covers techniques and advances in modern hair restoration.
19 citations
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April 2014 in “Hormones” Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
September 2024 in “Frontiers in Genetics” In this study, researchers found a significant association between the rs13405699 SNP at 2q31.1 and male pattern baldness among Han Chinese men, suggesting genetic influence on this condition in this population.
This review suggests that blood pressure differences among Afro-Caribbean and African communities may involve genetic factors as much as, or more than, salt intake, with no new clinical results reported.
Male pattern baldness is a common hair loss in men caused by genetics and hormones, with treatments including drugs, hair transplants, and hair loss products.
30 citations
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July 2017 in “Stem cells and cloning” This study found that scalp injection of fat enriched with stem cells may offer a promising alternative for treating early genetic alopecia in both men and women.
12 citations
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September 2021 in “PLoS ONE” In this study, researchers found that interaction between transcription factor EBF1 and gene WNT10A, influenced by a genetic variant, may play a role in hair shaft formation and anagen shortening in male pattern baldness.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found weak epidemiological associations between male pattern baldness and coronary heart disease, but no significant genetic link, though specific loci shared risks with other conditions.
15 citations
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April 2003 in “Journal of Dermatological Science” This study found no significant associations between the polymorphisms of SRD5A1 and SRD5A2 genes and androgenetic alopecia, clinical types of baldness, or response to finasteride in Koreans.
January 2018 in “Genetic engineering & biotechnology news” A genetic mutation linked to longer life and less disease was found in the Amish, and a drug is being developed to replicate these benefits.
42 citations
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April 2009 in “Human Genetics” This study suggests that the AGA risk haplotype in Europeans was driven to high frequency by positive selection, likely associated with a variant in the EDA2R gene.
1 citations
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February 2009 in “Clinical Genetics” This study identified new genetic variants on chromosome 20p11 associated with male pattern baldness.
68 citations
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March 1965 in “The BMJ” Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
3 citations
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June 2015 in “CRC Press eBooks” This article discusses the genetic and hormonal factors contributing to male pattern hair loss but reports no new experimental results.
In a human genetic study on hidradenitis suppurativa, researchers identified 12 genetic risk loci and found that CXCR4-CD74 signaling may play a key role in hair follicle inflammation, suggesting CXCR4 blockade as a potential therapeutic approach for this condition.
January 2025 in “Open Science Framework” This abstract outlines the genetic and biological processes of hair growth, highlighting that various hair disorders can have significant medical, aesthetic, and psychological impacts, though specific research findings or results were not reported.
June 2018 in “Advances in Cosmetic Surgery” Hair loss caused by genetics and hormones; more research needed for treatments.
8 citations
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October 1988 in “Clinics in dermatology” This paper discusses the lack of a genetic model for androchronogenic alopecia in rodents, noting the stumptailed macaque as a better current model due to its similarities to human male-pattern baldness; it reports no new results.