research Keratins and Skin Disease: Genetic and Molecular Roles
Keratin mutations cause skin diseases and could lead to new treatments.
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180-210 / 1000+ resultsresearch Premature Aging Syndromes: From Patients to Mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research Rapamycin But Not Acarbose Decreases Age-Related Loss of Outer Hair Cells in the Mouse Cochlea
Rapamycin reduces age-related hearing cell loss in mice, but acarbose does not.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Genotype Triad for HOTAIR rs10783618, LINC-ROR rs1942347, and MALAT1 rs3200401 as Molecular Markers in Systemic Lupus Erythematosus
Certain genetic markers can indicate higher or lower risk for systemic lupus erythematosus.
research A Hairy Situation: PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
research Cell Type-Specific Actions of Thyroid Hormones in Nonalcoholic Steatohepatitis and Liver Fibrosis
Targeting thyroid hormone receptor α in liver cells may help treat liver fibrosis.
research Bio-Pulsed Stimulation Effectively Improves the Production of Avian Mesenchymal Stem Cell-Derived Extracellular Vesicles That Enhance the Bioactivity of Skin Fibroblasts and Hair Follicle Cells
Bio-pulsed stimulation increases production of beneficial vesicles from bird stem cells that improve skin and hair cell functions.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.
research The Synergistic Effect of Phototherapy and Active Substances on Hair Growth
Combining light therapy with certain substances improves hair growth in people with hair loss.
research Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies
CRISPR/Cas9 has improved precision and control but still faces clinical challenges.
research Deciphering the Molecular Mechanisms of Stem Cell Dynamics in Hair Follicle Regeneration
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
research Phenotypic Heterogeneity in Human Genetic Diseases: Ultrasensitivity-Mediated Threshold Effects as a Unifying Molecular Mechanism
Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
research Loss of TET2 Tips the Scales Toward Tumorigenesis
Loss of TET2 increases the risk of skin and oral cancer.
research Emerging Interactions Between Skin Stem Cells and Their Niches
Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
research The Immunology of the Porcine Skin and Its Value as a Model for Human Skin
Porcine skin is very similar to human skin, making it a useful model for research.
research Vitamin D: More Than a Bona Fide Hormone
Vitamin D is important for bones, hair, blood pressure, and breast development.
research The Expanding Significance of Keratin Intermediate Filaments in Normal and Diseased Epithelia
Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Wnt signaling is crucial for skin development and hair growth.
research PRC2 Preserves Intestinal Progenitors and Restricts Secretory Lineage Commitment
PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
research Protein Microarrays: Analytical and Functional Applications in Biochemistry and Molecular Biology
Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.
research Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer
The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Haplotypes Spanning Centromeric Regions Reveal Persistence of Large Blocks of Archaic DNA
Ancient DNA blocks are still present in human genomes, possibly due to advantages they provide.
research Scientific Opinion on the Tolerable Upper Intake Level for Selenium
Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.
research Co-Factors of LIM Domains (Clims/Ldb/Nli) Regulate Corneal Homeostasis and Maintenance of Hair Follicle Stem Cells
Clim proteins are essential for maintaining healthy corneas and hair follicles.
research Commonalities Between COVID-19 and Radiation Injury
Some drugs may help treat both COVID-19 and radiation injury.
research Toxicology and Pharmacology of Botulinum and Tetanus Neurotoxins: An Update
Botulinum and tetanus neurotoxins are better understood now, with updated information on their effects and treatment.
research Molecular Targeted Agents and Biologic Therapies for Non-Small Cell Lung Cancer
New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.
research The Origins of Skin Diversity: Lessons From Dermal Fibroblasts
New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.