Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study discusses the effects of collagen hydrolysates and the dipeptide Pro-Hyp on gene expression related to hair and epidermis development in mouse skin and reports no new clinical results.

Hair transplantation successfully treated hair loss in a patient with Trichorhinophalangeal syndrome.

This study found that the polyurethane-cellulose acetate scaffold containing plasma rich in growth factors enhanced gene expression linked to wound healing compared to controls.

This study found that a polyurethane-cellulose acetate scaffold with plasma rich in growth factors may enhance gene expression related to wound healing in an experimental setting.

This study found that a cell therapy product, RCS-01, was well tolerated in aged skin and led to significant increases in gene expression related to extracellular matrix homeostasis, although the small cohort size limited further efficacy analysis.

This study found that overexpressing the gene Thymosin β4 (Tβ4) can promote the growth and development of secondary hair follicle dermal papilla cells in cashmere goats, suggesting its potential as a target for increasing cashmere production.

This study found that linc-PINT expression was significantly decreased in patients with atrial fibrillation compared to healthy controls, while several TGF-β signaling genes were increased, suggesting a potential role in heart arrhythmias' pathogenesis.

This study found that hepatic KRT79 expression is regulated by PPARA and is significantly associated with liver stress, suggesting it may serve as a diagnostic marker for liver diseases.

This study found that colorectal cancer patients could be categorized into two groups based on mitochondrial-related gene features, with distinct survival outcomes and tumor microenvironment characteristics, suggesting these features could inform individualized treatment plans.

This study found that, despite confirming MC1R expression and functional cAMP signalling, α-MSH treatment did not alleviate UVA-induced stress in adult dermal fibroblasts, suggesting that α-MSH-MC1R may not directly protect against UVA-induced photoaging in these cells.

This study found that the trichogenicity of cultured human outer root sheath follicular keratinocytes decreased with longer cultivation periods and was significantly influenced by the expression of the transcription factor FOXA2.

In this study, researchers identified ten key genes involved in the periodic development of hair follicles in cashmere goats, highlighting the importance of the Wnt signaling pathway and cell cycle in this process.

This study identified shared genes and pathways in idiopathic pulmonary fibrosis patients with COVID-19, suggesting these may increase mortality and pointing to potential drug targets for treatment.

This study identified key genes involved in feather follicle development in Wannan chickens, finding that genes such as LAMC2, COL6A3, and WNT7A are crucial in the regulation processes, potentially aiding molecular breeding programs for improved carcass appearance traits.

In this study, researchers identified 173 differentially expressed genes in alopecia areata patients linked to immune and hair follicle pathways, constructed a regulatory network involving mRNA, miRNA, and lncRNA, and highlighted CD8A and FOXD2-AS1 as potential diagnostic markers and therapeutic targets.

In this study, researchers identified key lncRNAs and target genes potentially involved in the transformation of the hair follicle cycle, which could advance understanding of lncRNAs' roles in hair follicle development.

In this study, a computational analysis of promoter regions in human fertility-related genes identified several new candidate regulatory motifs, but these require further experimental validation due to the limitations of being an in silico examination.

This study reports that milk goats exhibit significantly more differentially expressed genes related to hair follicle cycling across different months compared to cashmere goats, especially in December.

The research found that while Dnmt3a and Dnmt3b are not necessary for skin homeostasis in mice, the loss of Dnmt3a increases squamous tumor formation from carcinogens, and combined deletion of both results in more aggressive and metastatic tumors.

This study found that Pygo2 is crucial for early intestinal hyperproliferation induced by stabilized β-catenin, suggesting it as a potential target for therapeutic intervention in cancers with β-catenin mutation.

This study found that the DNA methylation status of skin samples from cashmere goats was higher during the telogen stage compared to the anagen stage, identifying genes potentially important for hair follicle development and growth.

In this study, the authors used AI-driven methods to identify and prioritize promising therapeutic targets that may address both aging and Glioblastoma Multiforme, proposing CNGA3, GLUD1, and SIRT1 as novel candidates.

This review examines the genetic challenges in improving wool and cashmere fibers, emphasizing the need for further research on wool keratins and keratin-associated proteins to enhance fiber characteristics.

This study examined noninvasive tissue samples, including buccal swabs, hair follicles, saliva, and urine cell pellets, and found hair follicles and urine cell pellets promising for transcriptomic and clinical analyses due to their sample quality and performance in disease-relevant applications.

Among families with pediatric brain disease, this study identified over 200 novel genetic causes, revealing potential treatment points using drug repurposing or nutritional supplementation.

This review examines over 271 candidate genes associated with economic traits in goats, highlighting their potential use in genetic markers and future breeding programs, and reports no new experimental results.

In this study, finasteride was found to reduce cholesterol levels and delay atherosclerosis in LDL receptor-deficient mice, and men using finasteride reported lower cholesterol levels, suggesting potential cardiovascular benefits by improving lipid profiles.

This study found that JAK1 and JAK3 inhibitors effectively reversed alopecia in a mouse model of AA by reducing skin inflammation, while JAK2 inhibition did not promote hair regrowth.

3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.

This study mapped the genome-wide epigenetic landscape in secondary hair follicle stem cells of goats, revealing distinct histone modification signatures associated with cashmere fiber cycling during different stages of hair growth.