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This research investigated immune cell involvement in various types of inflammatory alopecia by analyzing gene expression data from scalp samples, revealing distinct cellular changes in conditions like Alopecia Areata, Frontal Fibrosing Alopecia, Lichen Planopilaris, and Central Centrifugal Cicatricial Alopecia, which may inform future therapeutic targets.

In this study using a mouse model, researchers found that expressing Lef1 in dermal fibroblasts may enhance skin regeneration without affecting normal development.

This study identified downstream genes regulated by androgen receptor signaling in dermal papilla cells and suggests potential molecular targets for treating androgenetic alopecia and prostate cancer.

This study outlines the Human Gene Correlation Analysis tool, which classifies human genes by coexpression levels and identifies overrepresented annotation terms in correlated gene groups, with no new clinical results reported.

This study identified 374 eQTLs in scalp hair follicles associated with genes involved in metabolic, mitotic, immune processes, and responses to steroid hormones, contributing insights into genetic variation and hair traits.

This phase Ib study found that combining pegylated liposomal doxorubicin and pembrolizumab was well-tolerated and effective, with durable antitumor responses and a median survival of over two years in heavily pretreated ER-positive metastatic breast cancer patients.

This study identified seven genes that may serve as biomarkers for diagnosing skin cutaneous melanoma by analyzing the relationship between UV exposure, ferroptosis, and the cancer's pathology.

This study found that the transcription factor Meis2 is crucial for the maturation and innervation of sensory neurons responsible for light touch in mice, with its absence leading to reduced touch sensitivity.

This study found that NGAL expression increased in calcium-induced keratinocyte differentiation in vitro and was highly elevated in psoriasis-like skin conditions and skin cancers, suggesting a role in skin hyperplasia and homeostasis.

This study found that oral collagen peptides increased expression of genes associated with epidermis development and the hair cycle in hairless mice, providing insights into their potential skin benefits.

This study found that stimulating the olfactory receptor OR2AT4 in human hair follicles with a synthetic sandalwood odorant promotes hair growth ex vivo by decreasing apoptosis and increasing IGF-1 production.

This study found thousands of differentially expressed genes and proteins that may be associated with wool growth, suggesting potential gene families involved in hair growth regulation.

This study found that oral collagen peptides increased the expression of genes related to epidermal and hair cycle development in hairless mouse skin.

This study identified gene expression patterns in a mouse model that may influence tumor susceptibility and tissue functions related to inflammation and cell proliferation, highlighting Lgr5 and the vitamin D receptor as key regulators.

This study identified a gene expression signature in mouse embryonic dermal fibroblasts that depends on Wnt/β-catenin activity, potentially influencing dermal fibroblast identity and function.

This study identified shared gene expression changes and immune cell infiltration patterns that may contribute to hair loss in alopecia areata and cutaneous lupus erythematosus, but also highlighted factors that might preserve hair in psoriasis patients.

This study found rapid changes in gene expression in mouse skin cells from the fetal to early postnatal stages, identifying specific markers for different fibroblast types and driver genes in dermal cell differentiation.

This study identified morphotype-specific gene expression patterns in feathers, enhancing understanding of the molecular and cellular processes involved in feather development and diversification.

This study examined variations in epidermal thickness and protein expression across different dog breeds, finding significant differences by anatomical site and breed, with associated mRNA and protein expression changes observed.

This review discusses the structural knowledge of wool keratin proteins and genes, reports no new findings, and highlights promising directions such as keratin gene regulation.

This hypothesis paper suggests that PCOS may result from genetically determined ovarian hypersecretion of androgens, influencing hormone regulation and insulin resistance, with obesity further affecting its severity; no new clinical results are reported.

This study found that the activation of ER‑β increased keratinocyte proliferation and gene expression related to epidermal regeneration, enhancing wound healing in both cell models and rats.

In this study, researchers found that changes in immune cell infiltration and immune-related gene expression may contribute to the immune microenvironment changes in male androgenetic alopecia.

This study found that platelet-rich plasma may influence the proliferation of human hair dermal papilla cells by affecting gene expression related to the cell cycle.

This study found that spaceflight may induce skin health risks in astronauts by causing DNA damage and mitochondrial dysregulation, while also identifying gene expression changes that help re-adaptation after returning to Earth.

This study found that targeting S1PR1 signaling in mouse aortic endothelial cells helps suppress inflammation-related gene expression while revealing diverse and spatially distinct endothelial cell subtypes.

In this study, researchers developed a simple, non-invasive method to monitor circadian gene expression using whole hair root cultures, finding that elderly dementia patients' peripheral clocks still oscillate similarly to younger, healthier individuals, which suggests cellular senescence minimally affects some aspects of circadian rhythms.

This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.

In this study, college students with an evening chronotype were found to be at greater risk for androgenetic alopecia, potentially due to altered circadian rhythms as indicated by shifts in heart rate patterns and clock gene expression in hair follicles.

Organ transplant recipients have a higher risk of skin cancer over time, atopic dermatitis skin shows unusual bacterial and fungal patterns, a new tool for measuring hidradenitis suppurativa severity was created, and gene expression changes in male baldness suggest new treatments.