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    Glossary Gefitinib

    inhibits EGFR to treat certain non-small cell lung cancers

    Gefitinib, also known as Iressa, is a medication used to treat certain types of non-small cell lung cancer. It works by inhibiting the epidermal growth factor receptor (EGFR), which is involved in the growth and spread of cancer cells. By blocking this receptor, gefitinib can help slow down or stop the progression of the cancer.

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    1. Nonscarring inflammatory alopecia associated with the epidermal growth factor receptor inhibitor gefitinib Journal of the American Academy of Dermatology · 2006 · 57 citations
    2. Gefitinib: an adverse effects profile Expert opinion on drug safety · 2006 · 44 citations
    3. Erosive Pustular Dermatosis of the Scalp-Like Eruption due to Gefitinib: Case Report and Review of the Literature of Alopecia Associated with EGFR Inhibitors Dermatology · 2012 · 36 citations
    4. Trichoscopic Findings of Erosive Pustular Dermatosis of the Scalp Associated with Gefitinib Case Reports in Dermatology · 2017 · 21 citations
    5. Gefitinib-induced hair alterations: Figure 1 BMJ Case Reports · 2009 · 7 citations
    6. Severe Refractory Scarring Alopecia Associated With Combinational Use of Ficlatuzumab (AV-299) and Gefitinib Journal of Clinical Oncology · 2013 · 6 citations
    7. Erosive pustular dermatosis of the scalp induced by gefitinib: case and review of the literature Dermatology Online Journal · 2021 · 5 citations
    8. The Dark Side of Gefitinib: Reflectance Confocal Microscopy Applied to Hair Hyperpigmentation Skin Appendage Disorders · 2019 · 4 citations
    9. An unusual terminal hair growth on the nose tip associated with gefitinib therapy British Journal of Dermatology · 2007 · 4 citations
    10. Hair Growth After Gefitinib Treatment Clinical Oncology · 2005 · 2 citations
    11. Unexpected hair growth induced by gefitinib treatment in two patients with EGFR gene mutation-positive adenocarcinoma of the lung 2015 · 1 citations
    12. Severe scarring alopecia associated with combinational use of ficlatuzumab and gefitinib: a clinical and immunohistochemistry study Journal of dermatological science · 2012 · 1 citations
    13. Epidermal growth factor receptor inhibitor Geftinib-induced erosive pustular dermatosis of the scalp – A report with a brief review of the literature Journal of Skin and Sexually Transmitted Diseases · 2023
    14. Oral Combination Treatment of Gefitinib (IressaTM) and Sasam-Kyeongokgo: Synergistic Effects on the NCI-H520 Tumor Cell Line Applied sciences · 2023
    15. 증례 : Gefitinib에 의해 유발된 반흔성 탈모증 대한피부과학회지 · 2013
    16. Gefitinib Reactions Weekly · 2005
    17. Tyrosine Kinase Inhibitors – A Review on Pharmacology, Metabolism and Side Effects Current drug metabolism · 2009 · 508 citations
    18. Anti-EGFR mechanism of action: antitumor effect and underlying cause of adverse events. PubMed · 2006 · 91 citations
    19. Safety Profile of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors: A Disproportionality Analysis of FDA Adverse Event Reporting System Scientific Reports · 2020 · 58 citations
    20. Scarring alopecia associated with the epidermal growth factor receptor inhibitor erlotinib Journal of the American Academy of Dermatology · 2011 · 32 citations
    21. Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia PLoS ONE · 2013 · 20 citations
    22. Erlotinib-Associated Alopecia in a Lung Cancer Patient Journal of Thoracic Oncology · 2007 · 8 citations
    23. “PRIDE” Complex Indian Journal of Drugs in Dermatology · 2019 · 3 citations
    24. “Arrow” sign: A rapid microscopic diagnosis of hair change associated with epidermal growth factor receptor inhibitors Journal of the American Academy of Dermatology · 2013 · 3 citations
    25. Dermatologic adverse events in EGFR-TKIs: A real-world analysis. Journal of Clinical Oncology · 2024
    26. PRIDE syndrome with lumbosacral hypertrichosis Dermatology Review · 2022
    27. Non-small cell lung carcinoma spheroid models in agarose microwells for drug response studies Lab on a Chip · 2022 · 45 citations
    28. Molecular Targeted Agents and Biologic Therapies for Non-small Cell Lung Cancer Journal of thoracic oncology · 2010 · 12 citations
    29. The ophthalmological complications of targeted agents in cancer therapy: what do we need to know as ophthalmologists? Acta ophthalmologica · 2012 · 54 citations
    30. Target-Adverse Events and Fear of Cancer Progression, Anxiety, and Depression in Patients with Advanced Non-Small Cell Lung Cancer Research Square (Research Square) · 2021