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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Matrix effects in LC-MS can be managed but not completely avoided.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Adding chemotherapy to tamoxifen improves survival for older breast cancer patients with positive nodes.

Removing part of the vitamin D receptor stops vitamin D from working properly.

YAP and TAZ are crucial for skin cell growth and repair.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

There is no standardized treatment for hidradenitis suppurativa, and individualized plans are needed.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

Common variants in the Trichohyalin gene are linked to straight hair in Europeans.

FPHL affects hair density and diameter, causing visible hair loss in older women.

Activating the Sonic hedgehog gene in mice can start the hair growth phase.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

The Rotterdam Study aims to understand various diseases in older adults.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Lactate production is important for activating hair growth stem cells.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Dabrafenib was effective and well tolerated in treating thyroid cancer with a specific mutation.

A man with severe hair loss and skin disease regrew his hair with no side effects after taking tofacitinib.