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Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Estrogen therapy can reduce skin aging but has cancer risks.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Too much male hormone is the main cause of Polycystic Ovary Syndrome.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.

New treatments for male hypogonadism are effective and should be personalized.

Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Genetics and hormones cause hair loss; finasteride treats it safely.

Testosterone may slow down wound healing and increase inflammation.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

All three treatments reduce hirsutism, but spironolactone works best long-term.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.