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This study reports that aging in human skin involves early photo- and inflammation-related cellular changes, and suggests restoring KLF6 and HES1 expression might reverse some of these age-associated changes.

This study described the clinicopathological features of patients with frontal fibrosing alopecia who underwent skin biopsies.

This study found that K17 is crucial for the structural integrity and survival of hair-producing cells, with K17 null mice developing alopecia due to hair fragility and follicular alterations.

This chapter reviews trichoscopic-pathologic correlations in Frontal Fibrosing Alopecia and reports no new clinical results; the authors discuss genetics, clinical patterns, and unusual variants associated with this condition.

This article reports on a family with six members diagnosed with monilethrix, highlighting varying degrees of alopecia linked to this rare hair shaft defect.

This review examines how male facial anatomy and behavior contribute to sexual dimorphism in facial aging, pointing to factors that accelerate aging in men but presents no new clinical results.

This case report describes a young girl with trichothiodystrophy and suggests the need for early diagnosis and multidisciplinary interventions for her educational challenges.

This study found that GTx-024 significantly increased total lean body mass and improved physical function in healthy elderly men and postmenopausal women, suggesting potential use for muscle wasting conditions.

This study discusses how testosterone exerts its effects directly or through conversion to metabolites, DHT and estradiol 17β, each influencing different physiological processes, noting that DHT conversion is necessary for certain effects but not for muscle, bone, or erythropoiesis impacts.

This study diagnosed a group of six girls with various ectodermal abnormalities, identifying cranio-skeletal malformations consistent with focal dermal hypoplasia (Goltz syndrome), and found heterozygous mutations in the PORCN gene in two children.

This review discusses the potential of secretome derived from stem cells for treating alopecia areata and reports no new clinical results; the authors suggest the need for further human trials.

This document reviews various studies presented at the Plastic Surgery Research Council (PSRC) Annual Meetings and reports no new research findings; it discusses topics ranging from reconstructive techniques to gender-affirming surgeries.

In this study using rats, finasteride-induced DHT deficiency led to morphological changes in seminiferous tubules, linked with altered junctional protein expression, potentially impairing fertility.

In this study, mini rats with reduced growth hormone and insulin-like growth factor-1 levels exhibited distinct differences in skin thickness and hair cycle compared to standard Wistar rats, suggesting potential use as an animal model for studying GH deficiency-related skin conditions.

In this study, silver foxes given a yeast "filtrate factor" supplement retained their fur and normal pelts, while those without it experienced fur loss and thymus abnormalities.

In this study, anabolic and catatoxic steroids were reported to prevent weight loss, tissue calcification, and cardiac necrosis in a rat model of disturbed calcium metabolism and progeria-like syndrome.

In this study, minoxidil treatment in aged mice increased elastin expression and improved aortic structure and function, suggesting its potential for arterial remodeling in aging.

This case report presents three sisters with familial frontal fibrosing alopecia, making it the 25th documented familial case, with treatment results observed in one sister.

This review discusses the genetic disorder, monilethrix, characterized by fragile, brittle hair and its inheritance patterns, and reports no new clinical results.

In this study, hair levels of zinc and chromium were associated with a reduced likelihood of age-related cognitive decline in centenarians and oldest-old adults, suggesting further research is needed on these elements' potential role in cognitive health among the elderly.

This case report highlights that inherited zinc deficiency can persist into adulthood and emphasizes the importance of selecting optimal chelating agents to improve oral zinc bioavailability.

This review discusses the prognosis and treatment options for hair shaft disorders, finding no studies but suggesting some disorders improve with specific treatments like minoxidil and retinoids, while gentle hair care remains essential.

In this study, hair shafts from trichothiodystrophy patients with ERCC2 mutations revealed abnormal cuticle structures and protein imbalances compared to normal hair shafts.

This study identified mutations in the STUB1 gene linked to hereditary cerebellar ataxia with cognitive impairment, revealing potential effects on protein function and patient symptoms, including accelerated aging.

Frontal fibrosing alopecia can affect men's beards and leads to permanent hair loss.

This study found that intermittent treatment with FTI lonafarnib and sulforaphane may be a promising therapeutic approach for children with Hutchinson-Gilford progeria syndrome, as it improved the cellular phenotype.

In this case report, a 38-year-old woman with Parry–Romberg syndrome displayed left-sided facial atrophy and subclinical central nervous system involvement detectable by neuroimaging, suggesting that even symptom-free cases may benefit from systematic brain evaluations.

This review discusses changes in hair follicle characteristics and stem cell dynamics as indicators of aging in mice, noting increased occurrences of white hairs and curved hair follicles at older ages.

Improving end-of-life care at home requires better coordination, communication, and support.

This article reports a case of trichothiodystrophy in a 7-year-old girl with sulfur deficiency in her hair, characterized by sparse, slow-growing hair and distinctive tiger tail banding under microscopy.