Monilethrix of the Scalp from Almost Normal Aspect to Total Alopecia: Variable Intrafamilial Expressiveness
July 2021
in “
Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia
”
Studysummary This article reports on a family with six members diagnosed with monilethrix, highlighting varying degrees of alopecia linked to this rare hair shaft defect.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Monilethrix is a rare hereditary hair shaft disorder characterized by hair fragility and hypotrichosis, often inherited in an autosomal dominant pattern with variable clinical expression. This case study reports on six family members across two generations with varying degrees of alopecia due to monilethrix. Diagnosis was confirmed through trichoscopy, revealing characteristic hair shaft abnormalities resembling beads in a rosary. The condition can range from nearly normal hair to total alopecia, with no definitive treatment available. Management focuses on minimizing hair trauma and informing patients about the hereditary nature and progression of the disease.
