Monilethrix of the Scalp from Almost Normal Aspect to Total Alopecia: Variable Intrafamilial Expressiveness

Monilethrix is a rare hereditary hair shaft disorder characterized by hair fragility and hypotrichosis, often inherited in an autosomal dominant pattern with variable clinical expression. This case study reports on six family members across two generations with varying degrees of alopecia due to monilethrix. Diagnosis was confirmed through trichoscopy, revealing characteristic hair shaft abnormalities resembling beads in a rosary. The condition can range from nearly normal hair to total alopecia, with no definitive treatment available. Management focuses on minimizing hair trauma and informing patients about the hereditary nature and progression of the disease.