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Oral minoxidil may help improve fragile hair.

This study highlights the interconnected emotional distress between patients with end-stage COPD and their family caregivers, emphasizing that both parties' functional and emotional variables influence each other's distress.

This review reports that nail changes such as onycholysis, thin nails, and brittleness are associated with thyroid disorders, highlighting their importance in the early diagnosis of these conditions.

This letter challenges Dr. Dubois' statement that nearly all patients with Raynaud phenomenon will develop a systemic disorder, arguing that many experience it without progressing to serious disease.

Hair damage shows as fragility, dullness, and discoloration, varies by ethnicity, and is worsened by cosmetic procedures and diseases.

This study suggests that LONRF1 may play a vital role in linking oxidative damage responses and tissue remodeling during wound healing, with distinct mechanisms in senescent and non-senescent cells.

This document outlines recommendations from an international panel on testosterone therapy for aging men with late-onset hypogonadism, emphasizing the need for careful assessment and monitoring due to limited long-term safety data.

This article reviews considerations and guidelines for testosterone therapy in older men with low testosterone levels but does not provide new clinical results, emphasizing the need for ongoing evaluation and careful management, particularly regarding risks related to prostate and cardiovascular health.

This study reports that TFM-4AS-1, a selective androgen receptor modulator, promoted bone and muscle growth with reduced effects on reproductive organs in ovariectomized rats.

This study found that targeting IL-17 signaling in aged skin reduces inflammation and delays age-related traits, suggesting a potential strategy to prevent age-associated skin ailments.

This study found that extracellular Granzyme B contributes to skin aging and impaired healing in ApoE knockout mice by degrading essential extracellular matrix components like decorin and fibronectin.

This review discusses various environmental pollutants and their potential role in promoting mitochondrial dysfunction, which may contribute to aging-related diseases, cancer, and other adverse health outcomes, but reports no new experimental results.

In this study, old age was concluded not to be a significant cause of hair loss, with most cases in the elderly appearing to be androgen-driven.

In this retrospective cohort study of individuals diagnosed with late-onset systemic lupus erythematosus after age 80, most were women, joint and skin issues were prevalent, average survival was 4.5 years, and men had notably lower survival rates with higher mortality.

Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.

This review discusses progeria, focusing on its pathogenesis, major symptoms, and management strategies, and includes a clinical case of a girl with the disease confirmed by genetic testing; it reports no new clinical results.

This study found that nutritional deficiencies and gastrointestinal abnormalities are uncommon in children with ichthyosis and growth failure, suggesting chronic hypovolemia may be more prevalent in this group.

This study identified a 69 bp deletion in the KRT75 gene as the cause of the frizzle feather trait in chickens, affecting feather curling.

In this study, researchers found that cochlear hair cell function declined with age in CBA/CaJ mice starting at 10 months, before detectable hearing loss, and was marked by a decrease in cell size and BK channel currents, without effect on MET currents.

This study identified sex-specific determinants for facial wrinkles, finding that age is the strongest factor and that lifestyle influences like smoking, alcohol use, and skin color differentially affect wrinkling in men and women.

This study found that inhibiting NF-κB Essential Modulator (NEMO) in senescent murine dermal fibroblasts successfully reduced key factors associated with the senescence associated secretory phenotype (SASP), highlighting its potential as a therapeutic target for aging-related diseases.

In this study on adult-onset, whole body Spry1/2/4 triple knockout mice, researchers observed endocrine abnormalities and no increased tumor incidence, despite similar food intake and motor function.

This report describes a new case of isolated trichothiodystrophy with characteristic brittle hair and suggests a simplified classification scheme for understanding sulfur-deficient hair disorders.

In this case series, four adults developed severe, disabling multisymptom illness potentially linked to fluoroquinolone use, which persisted and progressed even after discontinuation of the drug.

In this study, researchers found that mice lacking the transcription factor FOXC1 in their hair follicle stem cells had increased rounds of hair regeneration but experienced hair thinning due to impaired ability to maintain stem cell quiescence and adhesion.

In this case report, a 38-year-old woman with monilethrix, a hair shaft disorder, was found to have both hair fragility and androgenetic alopecia, highlighting the diagnostic and management challenges posed by coexisting hair conditions.

This study found that mitochondrial dysfunction due to Crif1 deficiency in hair follicle stem cells significantly slows the hair growth cycle in adult mice but does not impact the maintenance of HFSC populations.

This review discusses hormonal changes in aging men and suggests the need for more research on androgen supplementation and partial androgen deficiency, without presenting new clinical findings.

This study found that as Korean women age, their hair density, diameter, tensile strength, and lustre decline, while grey hair ratio and certain sterol contents increase, suggesting unique ageing features compared to women in other countries.

This study suggests that increased amounts of less stable disulfide conformers in hair shafts may be linked to the brittleness observed in trichothiodystrophy.