Raynaud Phenomenon and Long-Term Risks

    February 1976 in “ JAMA
    Ray W. Gifford
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    TLDR Most people with Raynaud's won't get serious diseases, but doctors should watch for signs over time; also, quick weight loss can cause hair loss.
    In a letter to the editor, Dr. Edmund Dubois suggested that patients with a long history of "Raynaud disease" are likely to eventually show signs of an underlying connective tissue or vascular disorder. However, Drs. Irwin J. Schatz and Ray W. Gifford Jr. disagreed, stating that many patients with Raynaud phenomenon do not develop serious systemic diseases and that suggesting otherwise could cause unnecessary concern. They emphasized that reassuring patients about the minimal likelihood of developing serious systemic illness is a key part of treatment. Dr. Dubois responded by acknowledging that while patients with only Raynaud phenomenon should not be told that their symptoms will definitely progress to a connective tissue disorder, physicians should be aware of this possibility during long-term follow-up. Additionally, the document briefly mentions a study on telogen effluvium, a condition of hair loss, which was observed in six patients following rapid weight loss from a drastic diet, suggesting that rapid weight loss should be considered a stressful event that can cause this type of hair loss.
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