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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.

Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Mouse Notch is important for determining cell roles in hair follicles.

Hair follicles are promising targets for delivering drugs effectively.

Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

The microemulsion delivered the dye deeper into the skin than the cream.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

We need more research on human hair follicle pigmentation, not just mouse models.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

New micelle solutions greatly improve skin delivery of certain antifungal drugs.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Human sebum can cause acne by clogging pores.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

The conclusion is that an algorithm using trichoscopy helps diagnose different types of hair loss but may need updates and a biopsy if results are unclear.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.

Acne keloidalis is a chronic skin condition on the back of the neck in young black men, needing surgery for severe cases.

Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.