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Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

Notch signaling disruptions can cause various skin diseases.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Red clover extract improved hair, skin, mood, sleep, and tiredness in postmenopausal women.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

The normal human prostate does not significantly affect blood DHT levels.

Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.

Fat cells are important for tissue repair and stem cell support in various body parts.

Ethosomes could improve how well skin treatments work, but more research is needed on their safety and stability.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.