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More research is needed to understand how testosterone is maintained in adult males.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Understanding skin structure and development helps diagnose and treat skin disorders.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.

The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.

Finasteride effectively treats baldness but may cause sexual side effects.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Signaling pathways are crucial for hair growth in goats.

Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.

Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.

Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.

Herbal home remedies can effectively treat hair loss with fewer side effects.

New therapies are being developed that target integrin pathways to treat various diseases.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Thyroid hormone may speed up wound healing and hair growth, but more research is needed to understand its role in skin repair and use as a treatment.

Various treatments help hair growth, but more research needed for safety and effectiveness.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

Collagen XVII is important for skin aging and wound healing.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.