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Tofacitinib is a potential alternative treatment for alopecia totalis, especially in patients with a shorter duration of the condition and more preserved hair follicles, but the overall response rate is low.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

Targeting specific miRNAs may help treat hair follicle issues caused by hydrogen peroxide.

Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.

Magnesium oxide-infused membranes help heal wounds faster by reducing inflammation and promoting skin and hair follicle growth.

Activating certain hair follicle cells could prevent hair loss from cancer treatments.

TYK2 inhibition may help treat alopecia areata by promoting hair growth and reducing immune response.

Changing hair follicle identity could potentially reverse balding.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

Constant-release melatonin reduces SOX21 gene expression in goats during the hair follicle resting phase.

K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.

Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.

Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.

The research developed methods to test drugs that could protect and restore hair follicle protection in a hair loss condition.

A new method can detect mutations in mice by observing changes in hair follicle cells.

New treatment using engineered nanovesicles in hydrogel improves hair growth by repairing hair follicle cells in a mouse model of hair loss.

COVID-19 may cause hair loss and scalp pain due to inflammation and changes in hair follicle receptors, but these symptoms typically resolve in 2 to 4 months.

Serenoa repens extract helps regrow hair and repair hair loss by activating certain cell growth pathways.

Immunizing goats against melatonin can temporarily change their cashmere growth cycles and increase fleece production.

Vitamin A may influence hair loss conditions like alopecia, but more research is needed to understand how.

Frontal Fibrosing Alopecia may be a complex condition linked to hormonal changes in women, not just a form of Lichen Planopilaris.

Hidradenitis suppurativa is a chronic skin condition more common in women, linked to genetics and lifestyle factors, and associated with various other health issues.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Alopecia areata is caused by the immune system attacking hair follicles.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.