research Formulation and Design of Finasteride Coated Microneedles
Finasteride-coated microneedles effectively deliver the drug with minimal scalp damage and high stability.
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180-210 / 1000+ resultsresearch Study on the Development of Nanosilica-Curcumin-Bromelain Complex and Its Activity on Fibroblast Cell Lines in Animal Models
The nanosilica-curcumin-bromelain complex speeds up wound healing and hair growth in burns.
research Normalization of Hair Growth in Sparse Fur-Abnormal Skin and Hair (SPF-ASH) Mice by Introduction of the Rat Ornithine Transcarbamylase (OTC) Gene
Introducing the rat OTC gene normalized hair growth in SPF-ASH mice.
research Development and Optimization of Spironolactone Nanoparticles for Enhanced Dissolution Rates and Stability
Nanoparticles with more oleic acid improved the delivery and stability of the drug spironolactone.
research Expression of Novel Keratin-Associated Protein 5 Genes in the Cuticle Layer of Human Hair Follicles
The study found nine new hair protein genes in human hair follicles.
research Facial Determinants of Female Gender and Feminizing Forehead Cranioplasty
Forehead modification greatly increases the perception of femininity and is a safe procedure.
research Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
research Diagnostic Criteria for PCOS: Is There a Need for a Rethink?
The conclusion is that there's a need for a new conference to establish stricter guidelines for diagnosing Polycystic Ovary Syndrome (PCOS).
research Minoxidil Regulates Aging-Like Phenotypes in Rat Cortical Astrocytes In Vitro
Minoxidil may help reduce aging effects in brain cells.
research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase Predominates in Human Sebaceous Glands
The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
research RNA Sequence Analysis of Dermal Papilla Cells’ Regeneration in 3D Culture
3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
research Functional Identification of the Phosphorylation Sites of Arabidopsis PIN-FORMED3 for Its Subcellular Localization and Biological Role
Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.
research Expression Analysis of the Type I Keratin Protein Keratin 33A in Goat Coat Hair
Keratin 33A is a key protein in goat winter coats, especially in high-producing breeds.
research 5α-Reductase Activity in the Human Hair Follicle Concentrates in the Dermal Papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures
Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
research Self-Assembled Chitosan Nanoparticles for Percutaneous Delivery of Caffeine: Preparation, Characterization, and In Vitro Release Studies
Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.
research Key Targets of Hormonal Treatment of Prostate Cancer: The Androgen Receptor and 5α-Reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
research The Role of Labrasol in the Enhancement of the Cutaneous Bioavailability of Minoxidil in Phospholipid Vesicles
Labrasol® in phospholipid vesicles improves minoxidil delivery to the skin, potentially aiding hair growth treatments.
research Gene Expression Signatures and ALADIN Score Correlate with Response of Alopecia Areata Patients to Treatment with JAK Inhibitors
The ALADIN score can predict how well patients with alopecia areata will respond to JAK inhibitor treatments.
research Montagna Symposium 2014: Skin Aging - Molecular Mechanisms and Tissue Consequences
The symposium concluded that understanding the molecular mechanisms of skin aging could lead to better clinical practices and treatments.
research Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome
Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
research Psoroptosis of Sheep and Wild Goats: Clinical Manifestation and Treatment Under Anthropobiocenosis
Treating sheep and wild goats with specific medications and bathing sheep was 100% effective against a contagious skin disease caused by mites.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Formulation and Evaluation of Hair Gel for the Treatment of Chronic Inflammatory Disorder Seborrheic Dermatitis
The HG3 hair gel is the most effective for treating seborrheic dermatitis.
research Pharmacognostic Standardization of Lawsonia Inermis L. Leaf
The research helps standardize Henna leaf for safe use in traditional medicine and hair care.
research Defining Chronic Wound Types in Recessive Dystrophic Epidermolysis Bullosa Patients for Clinical Outcome Assessment
The conclusion is that differentiating wound types in RDEB patients is important for clinical trials and understanding the disease.
![Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1](/images/research/ff6e6cbe-cb9c-4d11-87ef-671d28ffd4fa/small/15506.jpg)
research Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1
Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.
research Finasteride-Loaded Nano-Lipidic Carriers for Follicular Drug Delivery: Preformulation Screening and Box-Behnken Experimental Design for Optimization of Variables
Optimized carriers effectively deliver Finasteride for hair loss treatment.
research Application of Microneedling Associated with Hair Therapy in the Treatment of Male Androgenetic Alopecia
Microneedling with capillary therapy slightly improved hair growth.
research Genetic Variation in the Ovine KAP22-1 Gene and Its Effect on Wool Traits in Egyptian Sheep
Certain genetic changes in the KAP22-1 gene are linked to better wool quality in Egyptian sheep.