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      Extraskeletal Actions of Vitamin D

      research Extraskeletal actions of vitamin D

      119 citations , July 2016 in “Annals of the New York Academy of Sciences”
      This review examines the impact of vitamin D signaling in extraskeletal tissues and notes that expected benefits from animal and cell studies have not been consistently replicated in human clinical trials.
      Potassium Channel Therapeutics at the Bedside

      research K channel therapeutics at the bedside

      119 citations , June 2005 in “Journal of Molecular and Cellular Cardiology”
      This article reviews the therapeutic potential of potassium channel openers for various conditions related to metabolic distress but does not report new clinical results; it emphasizes the need for further research.
      Potassium Channel Openers: Pharmacological and Clinical Aspects

      research Potassium channel openers: pharmacological and clinical aspects

      119 citations , October 1992 in “Fundamental & Clinical Pharmacology”
      This review discusses the pharmacological properties and therapeutic potential of K+ channel opening compounds, noting their prospective use in treating cardiovascular and respiratory conditions, but reports no new results.
      Liposomes in Cosmeceuticals

      research Liposomes in cosmeceutics

      111 citations , March 2012 in “Expert Opinion on Drug Delivery”
      This review discusses the potential use of liposomal formulations to enhance the effectiveness of cosmeceutical delivery through the skin barrier, with no new clinical results reported.
      From Skin Microrelief to Wrinkles: An Area Ripe for Investigation

      research From skin microrelief to wrinkles. An area ripe for investigation

      108 citations , January 2003 in “Journal of Cosmetic Dermatology”
      This summary explains the different types of wrinkles, their causes, and their distinct microanatomical characteristics, noting that each type may respond differently to treatments.
      Therapeutic Anti-Inflammatory Potential of Formyl-Peptide Receptor Agonists

      research Therapeutic anti-inflammatory potential of formyl-peptide receptor agonists

      105 citations , August 2010 in “Pharmacology & therapeutics”
      This article explores the potential of formyl-peptide receptor 2 agonists as innovative anti-inflammatory drugs, highlighting their ability to mimic the body's natural inflammation response, but it presents no new clinical findings.
      Androgen Dependence of Hirsutism, Acne, and Alopecia in Women

      research Androgen Dependence of Hirsutism, Acne, and Alopecia in Women

      105 citations , January 2009 in “Medicine”
      This study found that ethinylestradiol and high-dose cyproterone acetate significantly reduced hirsutism scores and were effective for treating acne and alopecia in women with hyperandrogenism.
      Sensitive Skin

      research Sensitive skin

      94 citations , January 2016 in “Journal of the European Academy of Dermatology and Venereology”
      Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.
      Stratum Corneum Dysfunction in Dandruff

      research Stratum corneum dysfunction in dandruff

      93 citations , April 2012 in “International Journal of Cosmetic Science”
      This article discusses the role of stratum corneum disruption in dandruff and suggests that treatments improving scalp barrier integrity along with antifungal activity may be beneficial; it reports no new research findings.
      Contact Cooling of the Skin

      research Contact cooling of the skin

      92 citations , January 1999 in “Physics in Medicine and Biology”
      This study developed and validated a computational model to optimize skin precooling methods for minimizing thermal damage during laser procedures.
      BMP2 And BMP7 Play Antagonistic Roles In Feather Induction

      research BMP2 and BMP7 play antagonistic roles in feather induction

      88 citations , July 2008 in “Development”
      This study shows that BMP2 and BMP7 play complex, necessary roles in feather development by regulating dermal condensation formation, with BMP7 acting early as a chemoattractant and BMP2 halting cell migration.
      Physiological Functions of PP2A: Lessons from Genetically Modified Mice

      research Physiologic functions of PP2A: Lessons from genetically modified mice

      87 citations , July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research”
      This review discusses the essential roles and complex regulation of PP2A in various physiological processes and reports no clinical results; the authors highlight the need for further mouse model research to explore PP2A's therapeutic potential.
      Molecular Signaling in Feather Morphogenesis

      research Molecular signaling in feather morphogenesis

      85 citations , October 2006 in “Current opinion in cell biology”
      This article reviews advances in feather development and regeneration, including pattern formation, stem cell biology, and evolution, but presents no new experimental results.
      Building Epithelial Tissues From Skin Stem Cells

      research Building Epithelial Tissues from Skin Stem Cells

      84 citations , January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology”
      This article reviews recent advancements in understanding skin stem cells and their roles in maintaining epidermal homeostasis and repairing wounds, without presenting new experimental findings.
      Neurosteroids, Neuroactive Steroids, and Symptoms of Affective Disorders

      research Neurosteroids, neuroactive steroids, and symptoms of affective disorders

      82 citations , August 2006 in “Pharmacology, Biochemistry and Behavior”
      This review proposes focusing on relationships between neuroactive steroids and psychiatric disorder symptoms, rather than relying on traditional disorder classifications, and reports no new clinical findings.
      Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN

      research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN

      81 citations , November 2012 in “Journal of the National Cancer Institute”
      This study found that FLCN deficiency in mice muscles led to increased mitochondrial biogenesis and a metabolic shift towards oxidative phosphorylation, with a similar advantage observed in FLCN-null kidney cancer cells.
      Eating Disorders: Progress and Challenges

      research Eating Disorders: Progress and Challenges

      81 citations , January 2011 in “European Journal of Internal Medicine”
      This review updates on the understanding and management of eating disorders, noting substantial progress over 30 years but highlighting the need for revised classification, clarified pathogenesis, and improved treatments.
      Adverse Effects of Common Medications on Male Fertility

      research Adverse effects of common medications on male fertility

      77 citations , June 2015 in “Nature Reviews Urology”
      This article reviews the effects of various medications on male fertility, noting that while commonly used drugs can mostly have reversible impacts, conclusive human evidence remains limited.