July 2018 in “Journal of Oral and Maxillofacial Surgery” This review chronicles the history and evolution of oral and maxillofacial surgery over the past century, emphasizing advancements in office-based practice and the impact of technological and clinical innovations.
July 2018 in “Journal of The American Academy of Dermatology” This article discusses current visualization methods for assessing hair restoration therapy responses, noting imprecision in triangulated measurements and patient dissatisfaction with visible tattoos.
April 2018 in “Journal of Investigative Dermatology” In this first-in-human study, BLZ-100, an intraoperative fluorescent imaging agent, was administered to 21 patients before skin cancer surgery and was found to be well tolerated without serious adverse effects, suggesting its potential to help distinguish cancerous from non-cancerous tissue based on fluorescence.
June 2016 in “Indian Journal of Pharmacy Practice” This report suggests that fluvoxamine use may be associated with hair loss, as observed in a 28-year-old male whose condition improved after stopping the drug.
March 2014 in “Oxford University Press eBooks” This narrative review explores the failure of fludalanine as an orally active antibiotic and highlights valuable insights into problem-solving strategies in drug discovery, without reporting new clinical results.
In this case report, topical application of fluocinolone acetonide acetate ointment increased hair length and thickness in three family members with congenital hypotrichosis.
September 2012 in “The Egyptian Journal of Histology” In this study, flutamide at therapeutic doses caused significant histological changes in the testes and epididymis of adult albino rats, reducing androgen receptor immunoreactivity and increasing estrogen receptor immunoreactivity.
January 2011 in “Journal of The American Academy of Dermatology” A man developed a painful skin condition after multiple heart procedures involving radiation.
August 2009 in “Reactions Weekly” Finasteride caused breast enlargement in two men, which improved after stopping the medication.
May 2008 in “10th European Congress of Endocrinology” Flutamide alone is as effective as the combination with finasteride for treating hirsutism.
January 2007 in “Chinese journal of plastic surgery” In this study, researchers observed that sodium selenite may counteract the pro-apoptotic effects of sodium fluoride on human scalp hair follicle cells in vitro.
April 2005 in “World Journal of Pharmaceutical and life sciences” This article discusses the formulation and evaluation of hair gels that may improve the treatment and prevention of dandruff by providing longer-lasting effects compared to traditional shampoos and lotions, but it reports no new clinical findings.
January 2005 in “The Chinese Journal of Dermatovenereology” In this study, sodium fluoride at certain concentrations increased the MDA levels in cultured human hair follicles, while 0.01 mmol/L sodium selenite reduced this effect at lower fluoride concentrations.
January 2004 in “Chinese Journal of Aesthetic Medicine” This study found that sodium fluoride concentrations inhibited the growth of human hair follicles in vitro, while sodium selenite at a specific concentration mitigated its toxicity.
This study reports that melatonin influenced HaCaT cell proliferation, with high concentrations reducing DNA synthesis and low concentrations enhancing it after 24 hours.
December 1999 in “Evidence-based obstetrics and gynecology/Evidence-based obstetrics & gynecology” Flutamide worked better than finasteride for reducing excessive hair growth in women, but had more side effects.
This article reports a case where a man's hair regrew after treating actinic keratosis with fluorouracil, suggesting a possible unexpected effect of the treatment.
August 2002 in “Dermatologic Surgery” This study found that topical fluridil increased the anagen percentage in men with androgenetic alopecia without causing irritation or systemic side effects.
February 2022 in “Journal of Cosmetic Dermatology” In this study, a combination treatment of topical 2% flutamide and 5% minoxidil significantly improved hair density, hair thickness, and patient satisfaction more than 5% minoxidil alone in patients with androgenetic alopecia over six months.
May 2021 in “medical journal of mashhad university of medical sciences” This preliminary study found that combining 5% minoxidil with 2% flutamide was associated with increased hair thickness in patients with androgenetic alopecia compared to 5% minoxidil alone.
December 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Flutamide, an oral anti-androgen therapy, is effective in treating female pattern hair loss, even without systemic androgen excess.
This study found flutamide to be an effective long-term treatment for female pattern hair loss with improved alopecia scores and high compliance when using very low doses, though some potential for hepatic disorders was observed initially.
134 citations
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September 2008 in “Lasers in surgery and medicine” This study found that low fluence photoepilation with intense pulsed light targets the pigmented area of hair follicles, causing temporary hair loss by inducing a catagen-like state without severe follicle damage.
78 citations
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March 2004 in “Annals of Oncology” This study found that the combination of docetaxel, cisplatin, and 5-fluorouracil is active and feasible for treating squamous cell carcinoma of the head and neck, with dose level I recommended for further testing.
73 citations
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July 2013 in “The Journal of Sexual Medicine” This study observed that androgenic alopecia patients taking finasteride had altered neuroactive steroid levels and persistent depression symptoms even after stopping the treatment.
69 citations
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September 2006 in “Human Reproduction” This study found that CD45RO+ cells, a subtype of T lymphocytes, were notably reduced in the ovarian follicles of women with PCOS, which may contribute to the condition's pathogenesis.
61 citations
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April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” This study reports that men with androgenic alopecia experience altered neuroactive steroid levels associated with persistent depression symptoms even after stopping finasteride treatment.
54 citations
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November 2017 in “Scientific Reports” In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.
54 citations
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November 2014 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that combining low-fluence Q-switched Nd: YAG laser and intense pulsed light led to faster and more effective melasma treatment compared to using the laser alone, though recurrence still occurred.