TLDR Finasteride caused breast enlargement in two men, which improved after stopping the medication.
Two men, aged 19 and 43, developed unilateral gynaecomastia while being treated with finasteride 1 mg/day for male pattern hair loss. The 19-year-old experienced painful enlargement of his left breast after 7 months of treatment, which resolved completely 4 months after discontinuing finasteride; his hormone levels also normalized. When finasteride was reintroduced at a reduced frequency, the gynaecomastia did not recur. The 43-year-old developed painful gynaecomastia in his right breast 20 days after starting finasteride and reported decreased libido. His pain decreased 3 months after stopping the medication, but the breast enlargement persisted after 7 months.
77 citations,
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February 1999 in “Drugs in R & D” The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.
January 2020 in “Archives of urology” Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
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