Fluoxetine

August 2009 in “ Reactions Weekly ”

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finasteride male pattern hair loss gynaecomastia hormone levels libido Propecia

TLDR Finasteride caused breast enlargement in two men, which improved after stopping the medication.

Two men, aged 19 and 43, developed unilateral gynaecomastia while being treated with finasteride 1 mg/day for male pattern hair loss. The 19-year-old experienced painful enlargement of his left breast after 7 months of treatment, which resolved completely 4 months after discontinuing finasteride; his hormone levels also normalized. When finasteride was reintroduced at a reduced frequency, the gynaecomastia did not recur. The 43-year-old developed painful gynaecomastia in his right breast 20 days after starting finasteride and reported decreased libido. His pain decreased 3 months after stopping the medication, but the breast enlargement persisted after 7 months.

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