Effect of Fluorine and Selenium on MDA Level of Human Scalp Hair Follicle In Vitro

    January 2005 in “ The Chinese Journal of Dermatovenereology ”
    Xue Ying
    TLDR High fluoride increases damage in hair follicles, but low selenium can reduce this damage at lower fluoride levels.
    The study investigated the impact of fluorine and selenium on the lipid peroxide (LPO) level in human hair follicles in vitro. It was found that sodium fluoride at concentrations of 1 mmol/L and 10 mmol/L increased the malondialdehyde (MDA) content, indicating higher LPO levels, while 0.1 mmol/L did not have this effect. Additionally, 0.01 mmol/L sodium selenite was able to reduce the MDA increase caused by 1 mmol/L sodium fluoride but was ineffective against the increase caused by 10 mmol/L sodium fluoride. This suggested that sodium fluoride at certain concentrations elevated MDA levels, and low concentrations of sodium selenite could mitigate this effect at lower fluoride concentrations.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 13 results

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community Recently my cum taste weird and

      in Satire  124 upvotes 6 months ago
      Dutasteride may alter the taste of semen. Some users report changes in taste while on finasteride or dutasteride.

      community Cold showers = healthier scalp?

      in Chat  13 upvotes 1 year ago
      Cold showers may improve scalp health for some, reducing itchiness and dandruff, but may increase dandruff for others while improving hair texture. Individual experiences with cold showers and scalp health vary.

      community 4 months on 2.5 mg OM, no improvement

      in Minoxidil  6 upvotes 2 years ago
      After 4 months on oral minoxidil with no significant hair regrowth, a user is frustrated and considering alternative treatments since they can't take finasteride due to side effects. Suggestions include natural DHT blockers, lifestyle changes, and other hair care tips.

      community 6 months on topical dut (album linked)

      in Progress Pictures  22 upvotes 3 years ago
      The post and conversation are about a user's 6-month progress using topical dutasteride, 8% minoxidil, tretinoin, 2% ketoconazole shampoo, microneedling, oral finasteride, pumpkin seed oil, Vitamin D3, a men's multivitamin, rosemary oil, and 5% minoxidil foam for hair loss treatment.

    Similar Research

    5 / 584 results