Prospective Cohort Study on the Effects and Tolerability of Flutamide in Patients with Female Pattern Hair Loss

December 2013 in “ Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ”

Rodney Sinclair

flutamide female pattern hair loss oral anti-androgen therapy androgenetic alopecia systemic androgen excess female pattern baldness anti-androgen therapy

TLDR Flutamide, an oral anti-androgen therapy, is effective in treating female pattern hair loss, even without systemic androgen excess.

In 2011, Paradisi R and colleagues conducted a cohort study on the effects and tolerability of flutamide in patients with female pattern hair loss. The study provided evidence supporting the use of oral anti-androgen therapy, specifically flutamide, in treating female androgenetic alopecia, regardless of whether systemic androgen excess was identified. This research was significant as it suggested a change in the treatment guidelines for this condition, which were primarily based on expert opinion rather than controlled clinical trials. The researchers recommended trialling oral anti-androgen therapy in women with androgenetic alopecia.

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Prospective Cohort Study on the Effects and Tolerability of Flutamide in Patients with Female Pattern Hair Loss