research High-Resolution Structures of Mutants Affecting Access to the Ligand-Binding Cavity of Human Lipocalin-Type Prostaglandin D Synthase
Mutations in the enzyme don't significantly change how it binds to its specific substances.
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research Biological Profile of Cortexolone 17a-Propionate (CB-03-01), a New Topical and Peripherally Selective Androgen Antagonist
CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.
research Cyclophosphamide-Associated Acneiform Drug Eruption in a Patient with Multiple Myeloma
A patient's skin eruption was caused by the cancer drug cyclophosphamide and improved after stopping the drug.
research Chemical and Photo-Oxidative Hair Damage Studied by Dye Diffusion and Electrophoresis
Chemical treatments and light exposure damage hair proteins.
research Rational Investigations in the Diagnosis and Management of Women with Hirsutism or Androgenetic Alopecia
Diagnose and manage hair issues in women by checking medical conditions and using personalized treatments.
research A New Look at an Old Option in the Treatment of Early-Stage Prostate Cancer: Hormone Therapy as an Alternative to Watchful Waiting
Hormone therapy might be a proactive alternative to watchful waiting for early-stage prostate cancer, potentially improving survival without aggressive treatment downsides.
research Congenital Atrichia
Congenital atrichia is a rare condition where children are born without hair, and treatment is often ineffective.
research Prevalence and Some Risk Factors with Therapeutic Trial of Sheep Dermatophytosis in Egypt
Tioconazole cream is highly effective and easy to use for treating sheep dermatophytosis.
research Cardiovascular Profile of Pharmacological Agents Used for the Management of Polycystic Ovary Syndrome
Medications for PCOS don't seem to raise heart disease risk.
research Spatiotemporal Labeling of Melanocytes in Mice
The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
research Mitochondrial Dysfunction in Diabetic Neuropathy May Be Involved in the Development of Neuropathic Pain via a Reduction in Neurosteroid Synthesis
Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.
research Anti-Androgen Therapy in Female Adult Acne
Anti-androgens are safe and effective for treating moderate to severe adult female acne.
research Dermatological Medications and Local Therapeutics During Pregnancy
Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.
research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders
Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.
research Determination of Rat 5α-Reductase Type 1 Isozyme Activity and Its Inhibition by Novel Steroidal Oxazolines
New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
research Characteristic Microstructure of Curved Human Hair
Curved human hair has different structures on its convex and concave sides.
research Theoretical Evaluation of Twenty Cannabinoid Derivatives on Androgen Receptor or 5α-Reductase Enzyme
Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.
research Letter in Reply: Alopecia Areata After SARS-CoV-2 Vaccination
A woman developed alopecia after her second Pfizer vaccine but regrew her hair with treatment and had no issues after a booster shot.
research Kerion Celsi Due to Microsporum Audouinii: A Severe Form in an Immunocompetent Girl
A 9-year-old girl with a healthy immune system was successfully treated for a severe fungal scalp infection caused by Microsporum audouinii.
research Comparison of Wiping Methods for the Removal of Cleaning Agent Residue from Hair Follicles
All wiping methods are as effective as washing for removing cleaning agent from hair.
research Preparation, Optimization, In Vitro Evaluation and Ex Vivo Permeation Studies of Finasteride Loaded Gel Formulations Prepared Using Response Surface Methodology
The combination of propylene glycol and Tween® 80 improves finasteride gel effectiveness.
research Investigation of pH Effect on Cationic Solute Binding to Keratin and Partition to Hair
Solute binding to hair keratin is mainly driven by hydrophobic interactions and changes with pH.
research Development of a Novel Penetration-Enhancing Agent for Hair Products
HAIRCARECUBE TM (HCC) helps hair products work better by getting active ingredients deeper into the hair.
research Diagnosis and Treatments of Hirsutism: Where Are We?
Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.
research The Evaluation and Treatment of Hirsute Women
Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.
research Investigational Medications in the Treatment of Alopecia
New treatments for hair loss are being developed using molecular biology.
research Hirsutism And Hypertrichosis In Adults: Investigations And Treatment
The document concludes that treatment for excessive hair growth depends on the cause, with options including hair removal methods and medications like anti-androgens or insulin-sensitizing drugs.
research Alternative Therapies for Vitiligo
Some alternative therapies for vitiligo show promise but need more research.
research Effects of Dobutamine on Cyclic AMP Accumulation Induced by the Stimulation of Dopamine Receptors in Rabbit Retina In Vitro
Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.
research Production of Ultraviolet-Light-Induced Skin Erythema in the Hairless Rat: A Comparison with the Haired Rat in Screening for Anti-Inflammatory Drugs
Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.