January 2005 in “The Chinese Journal of Dermatovenereology” In this study, sodium fluoride at certain concentrations increased the MDA levels in cultured human hair follicles, while 0.01 mmol/L sodium selenite reduced this effect at lower fluoride concentrations.
January 2004 in “Chinese Journal of Aesthetic Medicine” This study found that sodium fluoride concentrations inhibited the growth of human hair follicles in vitro, while sodium selenite at a specific concentration mitigated its toxicity.
This study reports that melatonin influenced HaCaT cell proliferation, with high concentrations reducing DNA synthesis and low concentrations enhancing it after 24 hours.
December 1999 in “Evidence-based obstetrics and gynecology/Evidence-based obstetrics & gynecology” Flutamide worked better than finasteride for reducing excessive hair growth in women, but had more side effects.
December 1994 in “The American Journal of Cosmetic Surgery” This article reviews the current basic science of angiosome theory and flap delay, applying this knowledge to modern scalp flap procedures, without reporting any new clinical findings.
January 1994 in “JAPANESE JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS” Testosterone and fleece-flower root affect mouse hair growth.
February 1990 in “PubMed” This study observed that hirsute females displayed increased S-phase hair bulb cells and decreased G0/1-phase cells compared to healthy females, with a strong correlation between S-phase percentages and DHEA-S levels.
This article reports a case where a man's hair regrew after treating actinic keratosis with fluorouracil, suggesting a possible unexpected effect of the treatment.
February 2022 in “Journal of Cosmetic Dermatology” In this study, a combination treatment of topical 2% flutamide and 5% minoxidil significantly improved hair density, hair thickness, and patient satisfaction more than 5% minoxidil alone in patients with androgenetic alopecia over six months.
January 2022 in “Essentials in ophthalmology” This review discusses risk factors for intraoperative floppy iris syndrome, emphasizing tamsulosin and other α1 blockers, and underscores the importance of preoperative screening to mitigate surgical complications, but it reports no new results.
May 2021 in “medical journal of mashhad university of medical sciences” This preliminary study found that combining 5% minoxidil with 2% flutamide was associated with increased hair thickness in patients with androgenetic alopecia compared to 5% minoxidil alone.
March 2020 in “Upravlìnnâ, ekonomìka ta zabezpečennâ âkostì v farmacìï” This study developed quality control methods for the "Flavosterol" emulgel, which met the required quality standards and is intended for the prevention and treatment of androgenetic alopecia.
December 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Flutamide, an oral anti-androgen therapy, is effective in treating female pattern hair loss, even without systemic androgen excess.
This study found flutamide to be an effective long-term treatment for female pattern hair loss with improved alopecia scores and high compliance when using very low doses, though some potential for hepatic disorders was observed initially.
August 2002 in “Dermatologic Surgery” This study found that topical fluridil increased the anagen percentage in men with androgenetic alopecia without causing irritation or systemic side effects.
137 citations
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May 1984 in “Journal of Investigative Dermatology” Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.
134 citations
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September 2008 in “Lasers in surgery and medicine” This study found that low fluence photoepilation with intense pulsed light targets the pigmented area of hair follicles, causing temporary hair loss by inducing a catagen-like state without severe follicle damage.
87 citations
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April 1973 in “Endocrinology” This study found that in hamster flank organs, 17βC inhibited enlargement caused by topical testosterone but not by DHT, suggesting potential use in androgen-related skin disorders like acne.
80 citations
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November 2017 in “New Phytologist” In this study, the researchers used the dual-flow-RootChip to show that Arabidopsis roots can locally adapt their hair development in response to asymmetric phosphate conditions.
78 citations
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March 2004 in “Annals of Oncology” This study found that the combination of docetaxel, cisplatin, and 5-fluorouracil is active and feasible for treating squamous cell carcinoma of the head and neck, with dose level I recommended for further testing.
75 citations
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October 2002 in “Journal of Dermatological Science” This study found that Sophora flavescens extract may promote hair growth in mice by inducing earlier hair cycle changes and regulating growth factors in dermal papilla cells.
73 citations
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July 2013 in “The Journal of Sexual Medicine” This study observed that androgenic alopecia patients taking finasteride had altered neuroactive steroid levels and persistent depression symptoms even after stopping the treatment.
69 citations
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September 2006 in “Human Reproduction” This study found that CD45RO+ cells, a subtype of T lymphocytes, were notably reduced in the ovarian follicles of women with PCOS, which may contribute to the condition's pathogenesis.
63 citations
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May 2020 in “Advanced Healthcare Materials” In animal models, this study reported that a wound dressing combining quaternized chitin and silk fibroin significantly enhanced vascular reconstruction and hair follicle regeneration, approaching normal tissue levels.
61 citations
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April 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” This study reports that men with androgenic alopecia experience altered neuroactive steroid levels associated with persistent depression symptoms even after stopping finasteride treatment.
55 citations
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June 2007 in “Journal of Statistical Planning and Inference” This study introduces an extended approach to the Bonferroni procedure that accounts for correlations among endpoints, aiming to improve test power while maintaining strong control of the family-wise type I error rate in clinical trials.
54 citations
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November 2017 in “Scientific Reports” In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.
54 citations
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November 2014 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that combining low-fluence Q-switched Nd: YAG laser and intense pulsed light led to faster and more effective melasma treatment compared to using the laser alone, though recurrence still occurred.
53 citations
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October 2012 in “Journal of dermatological treatment” This study found that low-fluence 1064 nm Q-switched Nd:YAG laser treatment effectively improved melasma in Asian patients without serious side effects, achieving an average improvement rate of 50-74%.