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New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Both mouse and rat models are effective for testing alopecia areata treatments.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Key genes are crucial for Drosophila wing development and could be insecticide targets.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

FOXN1 gene variants cause low T cells and immune issues from birth.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Treating cystoid macular oedema in uveitis is difficult and risky.

Finasteride works better than Serenoa repens for male hair loss.

About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Despite progress in treatment, the exact cause of Alopecia areata is still unknown.

Intralesional triamcinolone acetonide is the most effective treatment for localized alopecia areata.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Skin symptoms are important for diagnosing and managing juvenile-onset systemic lupus erythematosus and usually get better with treatment.