research First-In-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
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research First Use of Thymus Transplantation Therapy for FOXN1 Deficiency (Nude/SCID): A Report of 2 Cases
Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.
research First-Line Therapy with Gemcitabine and Paclitaxel in Locally Recurrent or Metastatic Breast Cancer: A Phase II Study
Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.
research Lessons Learned from the First Decade of Laser-Assisted Drug Delivery
Laser-assisted drug delivery has shown improved treatment outcomes for skin conditions and has potential to reduce side effects and treatment time.
research First Symposium on Natural Gene Therapy of the Skin
Natural gene therapy shows promise for treating skin disorders like epidermolysis bullosa.
research Fire Needle Combined Therapy or Surgery for Neck Carbuncle? A Case Series
Fire needle therapy is an effective and better alternative to surgery for early-stage neck carbuncles.
research First Case of Degenerative Mucinotic Mural Folliculitis in Brazil
A cat in Brazil was found with a severe skin condition linked to feline AIDS.
research First-Degree Relatives of Patients With Systemic Lupus Erythematosus: Autoreactivity but Not Autoimmunity?
Relatives of lupus patients show signs of immune system activity but not full-blown lupus.
research First Report of 'Candidatus Phytoplasma Aurantifolia' Associated with the Invasive Weed Eclipta Prostrata in Taiwan
'Eclipta prostrata' plants in Taiwan are infected with 'Candidatus Phytoplasma aurantifolia'.
research First Two Cases of Alopecia Areata During Golimumab Therapy
Membership in a self-help organization is linked to being better informed and having a higher education, but it doesn't clearly affect disease outcomes.
research First Symposium of Ichthyosis Experts
Experts met to improve care for ichthyosis patients in Spain.
research Relationship Between Prepregnancy BMI and Concentrations of Iron, Calcium, and Magnesium in Serum and Hair During the First Trimester of Pregnancy in Women
Overweight or obese women before pregnancy have lower iron levels in their serum and hair during early pregnancy.
research Regulating the Wnt/Beta-Catenin Signaling Pathway Promotes Repigmentation in Vitiligo Using Fire Needle Therapy
Fire Needle Therapy may help bring back skin color in vitiligo by affecting cell growth signals.
research Clinical Research Progress of Fire Needle Acupuncture in the Treatment of Alopecia Areata
Fire needle acupuncture is effective for treating alopecia areata.
research The Efficacy and Safety of Fire Needle Therapy for Alopecia Areata: A Protocol for Systematic Review and Meta-Analysis
Fire needle therapy's benefits and safety for alopecia areata need more evidence.
research Gut Dysbiosis in Alopecia Areata Patients Reveals Overabundance of Firmicutes and Underrepresentation of Bacteroides
Alopecia Areata patients have too many Firmicutes and too few Bacteroides in their gut.
research First Case of V281+I172N/V281L CYP21A2 Genotype Associated with Congenital Adrenal Hyperplasia: A Case Report from Southern Italy
New genotype linked to non-classical congenital adrenal hyperplasia found in Italian siblings.
research First Reboxetine Trial Results Reported
Finasteride increased hair count and regrowth in men with hair loss but also caused more sexual side effects than placebo.
research The First Clinical Trial of Topical Application of Procyanidin B-2 to Investigate Its Potential as a Hair Growing Agent
Procyanidin B-2 lotion might help men grow thicker hair without side effects.
research Alpha-Spinasterol from Melandrium Firmum Attenuates Benign Prostatic Hyperplasia in a Rat Model
α-spinasterol from Melandrium firmum can help reduce prostate enlargement.
research The First Case Report of Kerion-Type Scalp Mycosis Caused by Aspergillus Protuberus
A rare fungal infection on a child's scalp was successfully treated with antifungal medication.
research Rapid Fire Hair Implanter Carousel: A New Surgical Instrument for the Automation of Hair Transplantation
The Rapid Fire Hair Implanter Carousel may allow faster hair transplants with less bleeding and similar healing and growth compared to manual methods.
research Naevus Trichilemmocysticus: The First Pediatric Case of a Newly Delineated Organoid Naevus
The first pediatric case of naevus trichilemmocysticus was documented.
research Genes and Immune Response in Alopecia Areata: Review of the Alopecia Areata Research Summit First Day Proceedings
Alopecia areata involves complex immune and genetic factors, with potential treatment targets identified, but more research is needed.
research The Expansion of Uterus Transplantation to Transgender Women
Doctors are preparing to potentially perform uterus transplants in transgender women, considering technical, hormonal, and ethical factors.
research The First Syntheses of 16β-Chloro- and 16β-Bromo-Cyproterone Acetate
Scientists made two new chemicals that might help treat diseases caused by male hormones.
research Melandrium Firmum Extract Promotes Hair Growth by Modulating 5α-Reductase Activity and Gene Expression in C57BL/6J Mice
Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.
research The First Broad Replication Study of SNPs and a Pilot Genome-Wide Association Study for Androgenetic Alopecia in Asian Populations
Two specific genetic markers increase the risk of hair loss in Asian populations.
research Case of Autosomal Recessive Woolly Hair/Hypotrichosis with Compound Heterozygous Mutations in the LIPH Gene at c.742C > A and c.614A > G: The First Japanese Case
The first Japanese case of a genetic hair disorder caused by specific mutations in the LIPH gene was identified.
research A First Case of Childhood Chronic Inflammatory Demyelinating Polyneuropathy Associated with Alopecia Universalis
A nine-year-old girl with muscle weakness and total hair loss improved with specific treatments.