TLDR Additional surgeries are often needed to fix facial issues in patients with orofacial clefts.
Secondary soft tissue defects in patients with orofacial clefts include scars, asymmetry, vermilion and white roll incongruencies, nasal deformities, and soft tissue volume deficiencies. Multiple surgeries before skeletal maturity can disrupt facial growth. This review discusses residual defects affecting the lip and their surgical management, noting that bilateral cleft lip patients may have additional specific deformities. Postoperative palate deformities can result from improper wound healing. Adjunctive aesthetic procedures are crucial for correcting these secondary deformities.
28 citations
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July 2013 in “Journal of Craniofacial Surgery” Hair follicle transplantation can hide scars but often needs more than one surgery for better results.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
2 citations
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January 2019 in “Medizinische Genetik” The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
30 citations
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May 2019 in “Medicinal Research Reviews” Combining stem cells and targeted treatments can improve muscle and skin healing after cleft repair.
20 citations
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November 2014 in “Developmental Dynamics” Palate formation and skin healing share similar biological processes.
A 12-year-old girl in Saudi Arabia with Focal dermal hypoplasia showed skin and dental symptoms, highlighting the condition's variability and the need for personalized treatment.
