research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
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research Male Androgenetic Alopecia
Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
research Male Androgenetic Alopecia
DHT, a testosterone byproduct, causes male pattern baldness.
research Anti-Androgenic Activities of Ganoderma Lucidum
Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
research Use of Oral Isotretinoin in the Treatment of Frontal Fibrosing Alopecia: Case Series
Oral isotretinoína effectively stabilizes frontal fibrosing alopecia.
research TSPO Activation Modulates the Effects of High Pressure in a Rat Ex Vivo Glaucoma Model
Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
research Anabolic Effects of Testosterone Are Preserved During Inhibition of 5α-Reductase
Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
research Inhibitory Influence of Agmatine on Catamenial-Like Seizure Susceptibility in Progesterone Withdrawn Female Rats
Agmatine may help reduce seizures linked to hormone changes in female rats.
research Pregnenolone for the Treatment of L-DOPA-Induced Dyskinesia in Parkinson's Disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Delivery of Minoxidil Encapsulated in Cyclodextrins with Photoacoustic Waves Enhances Hair Growth
Using photoacoustic waves to deliver minoxidil improves hair growth effectively and safely.
research The Anxiolytic-Like Effects of Estazolam on a PTSD Animal Model
Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.
research Effect of Castration and Finasteride on Urinary Oxalate Excretion in Male Rats
Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
Finasteride causes abnormal growth in male mice cells at high doses.
research The Effect of Minocycline on the Metabolism of Androgens by Human Oral Periosteal Fibroblasts and Its Inhibition by Finasteride
Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.
research Plant Extracts and Safflower Extract-Loaded Nanostructured Lipid Carriers for Hair Growth Promotion
Safflower extract in nanostructured carriers was more effective than minoxidil for hair growth without irritating skin.
research Alcohol Exposure During Late Adolescence Increases Drinking in Adult Wistar Rats, an Effect That Is Not Reduced by Finasteride
Alcohol in teen years leads to more adult drinking, finasteride doesn't help.
research Formulation and Characterization of Transethosomes for Enhanced Transdermal Delivery of Propranolol Hydrochloride
The new gel improves skin delivery of a drug, potentially reducing dose frequency and side effects.
research Hair Growth Activity and Safety Test of Ethosomal Gel Ethyl Acetate Fraction of Nothopanax Leaves (Nothopanax Scutellarium Merr.)
The 1% ethyl acetate fraction ethosomal gel from Nothopanax scutellarium leaves promotes hair growth but can mildly irritate the skin.
research Decreased Fertility in Male Rats Administered the 5α-Reductase Inhibitor, Finasteride, Due to Deficits in Copulatory Plug Formation
Finasteride reduces male rat fertility by causing issues with copulatory plug formation.
research Finasteride Administration Potentiates the Disruption of Prepulse Inhibition Induced by Forced Swim Stress
Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.
research Low-Level Laser Therapy for Treatment of Hair Loss
Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.
research Hair Disorders
Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
research Uromedic® Pumpkin Seed Derived Δ7-Sterols, Extract and Oil Inhibit 5α-Reductases and Bind to Androgen Receptor In Vitro
Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.
research A Combination Therapy for Androgenic Alopecia Based on Quercetin and Zinc/Copper Dual-Doped Mesoporous Silica Nanocomposite Microneedle Patch
The microneedle patch with quercetin, zinc, and copper effectively promotes hair regrowth for androgenic alopecia.
research Contribution of Androgens to Chronic Allograft Nephropathy Is Mediated by Dihydrotestosterone
Male hormones worsen kidney transplant damage, but blocking them helps.
research Hormesis And Medicine: Biphasic Dose-Response Relationship
Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
research The Hair Growth Promoting Effect of Sophora Flavescens Extract and Its Molecular Regulation
Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.
research Anti-Inflammatory and Anti-Hyperplastic Effect of Bazhengsan in a Male Rat Model of Chronic Nonbacterial Prostatitis
Bazhengsan reduces inflammation and tissue growth in chronic prostatitis.
research Poly(γ-Glutamic Acid)/Chitosan Hydrogel Nanoparticles for Effective Preservation and Delivery of Fermented Herbal Extract for Enlarging Hair Bulb and Enhancing Hair Growth
The nanoparticles improved hair growth and enlarged hair bulbs.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.