research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
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research Frontal Fibrosing Alopecia: A Review
Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
research Pharmacological Activation of Estrogen Receptors-α and -β Differentially Modulates Keratinocyte Differentiation with Functional Impact on Wound Healing
Activating ER-β, not ER-α, improves skin cell growth and wound healing.
research Stem Cells and the Skin
Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
research Interferons in Dermatology
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research A Guide to Studying Human Dermal Adipocytes In Situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
research The Use of Mesenchymal Stromal Cells in the Treatment of Coronavirus Disease 2019
Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
research Cutaneous Wound Healing: Canine Allogeneic ASC Therapy
Using stem cells from fat tissue can significantly improve wound healing in dogs.
research Secondary Cicatricial and Other Permanent Alopecias
The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
research The Etiology and Pathogenesis of Alopecia Areata
The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.
research A Systematic Approach to Afro-Textured Hair Disorders
Dermatoscopy helps diagnose hair and scalp disorders in people with Afro-textured hair, but more research is needed for better understanding and treatment.
research Female Pattern Hair Loss
Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
research Ptosis in Childhood: Causes, Clinical Presentations, and Management
Childhood ptosis can vary from a minor cosmetic issue to a serious condition and may signal other health problems.
research Hair Follicle Mesenchymal Stem Cell Exosomal LncRNA H19 Inhibited NLRP3 Pyroptosis to Promote Diabetic Mouse Skin Wound Healing
A substance from hair follicle stem cells helps heal skin wounds in diabetic mice by promoting cell growth and preventing cell death.
research Metabolic Dysfunction in Female Mice with Disruption of 5α-Reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
research Testosterone Reduces Tight Junction Complexity and Down-Regulates Expression of Claudin-4 and Occludin in the Endometrium in Ovariectomized, Sex-Steroid Replacement Rats
Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.
research Wnt Is Back in Drugmakers' Sights, but Is It Druggable?
Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.
research Accelerated Wound Healing Using Nanoparticles
Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.
research Controversy: Is There a Role for Adjuvants in the Management of Male Pattern Hair Loss?
Adjuvants, diet changes, and laser therapy may improve male pattern hair loss.
research Proposed Mechanisms of Low-Level Light Therapy in the Treatment of Androgenetic Alopecia
LLLT helps treat hair loss by increasing blood flow, reducing inflammation, and stimulating growth factors.
research A Comprehensive Review of Biochemical Factors in Herbs and Their Constituent Compounds in Experimental Studies on Alopecia
Herbs might help with hair loss, but more research is needed to confirm their safety and effectiveness.
research Alopecia Areata Universalis After Phenobarbital-Induced Anticonvulsant Hypersensitivity Syndrome
A 3-year-old boy lost all his hair due to a rare reaction to phenobarbital, but it grew back after steroid treatment.
research Frontal Fibrosing Alopecia: A New Autoimmune Entity?
Frontal Fibrosing Alopecia might be an autoimmune disease.
research Notch1 Signaling Regulates Wound Healing by Changing the Characteristics of Epidermal Stem Cells
Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
research Conditions Simulating Androgenetic Alopecia
Different hair loss types need accurate diagnosis for proper treatment.
research Evaluation of Apoptosis Regulatory Markers in Androgenetic Alopecia
Apoptosis may contribute to hair loss in androgenetic alopecia.
research Female-Patterned Alopecia in Teenage Brothers with Unusual Histologic Features
Two teenage brothers had a rare, treatment-resistant form of female-pattern hair loss with unusual scalp changes.
research Overexpression of Hypoxia-Inducible Factor-1α in Hidradenitis Suppurativa: The Link Between Deviated Immunity and Metabolism
Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
research Challenges in Diagnosing Female Pattern Hair Loss
Female pattern hair loss diagnosis is challenging and should use dermoscopy and histopathology instead of pattern recognition, as hormones may not always be the cause.
research 5α-Reductase Inhibitors: Progress and Therapeutic Potential
5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.