August 2024 in “Journal of Personalized Medicine” In this study using a rabbit model, higher incidences of intraoperative floppy iris syndrome were observed in animals given the α-blocker tamsulosin, suggesting a potential association with increased iris billowing during eye surgery.
This case report describes a 16-year-old girl with severe generalized gingival fibromatosis and hypertrichosis, who underwent successful treatment through gingivectomy, with uneventful healing observed over an eight-month follow-up.
January 2014 in “Revista del Hospital Juárez de México” The authors concluded that preoperative treatment with finasteride for a month effectively reduced perioperative bleeding and shortened hospital stays in patients undergoing transurethral resection of the prostate.
9 citations
,
August 2019 in “Clinical genitourinary cancer” This study suggests that 5-alpha reductase inhibitors may reduce invasive cancer features and improve survival in men undergoing radical cystectomy for high-grade urothelial carcinoma, although further research is needed to confirm these findings.
33 citations
,
February 2024 in “International Journal of Molecular Sciences” This study highlights the crucial, multifaceted roles of fibroblasts in wound healing and various diseases, including their dysregulation in diabetic foot ulcers, underscoring the need for targeted therapies to address complications and morbidity from such chronic conditions.
5 citations
,
January 2017 in “Acta Endocrinologica” This case report discusses a postmenopausal woman whose hyperandrogenism and metabolic symptoms improved significantly after the surgical removal of an ovarian Leydig cell tumor, confirmed post-operatively.
October 2024 in “Journal of the Endocrine Society” In this case report, the authors describe the diagnosis and management of a rare case of hyperandrogenism in a postmenopausal woman, attributed to coexisting ovarian Leydig cell and Brenner tumors, with improvement in symptoms following bilateral salpingo-oophorectomy.
December 2003 in “British Journal of Urology”
5 citations
,
June 2015 in “International Journal of Women's Dermatology” This article reviews hirsutism from an endocrine perspective and reports no new clinical findings.
1 citations
,
December 1998 in “PubMed” In this case report, a 68-year-old woman with a Leydig cell tumor of the ovary experienced virilization, and surgical removal led to normalization of testosterone levels and regression of symptoms.
December 2022 in “Journal of Medical Case Reports” This case report highlights the importance of considering an ovarian steroid cell tumor diagnosis in young women with increased testosterone after ruling out polycystic ovarian syndrome.
26 citations
,
March 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia” This review discusses the definition, causes, diagnostic strategies, and treatment options for hirsutism in women without reporting new clinical results, and highlights the impact of the condition on self-esteem.
January 2025 in “BMJ Case Reports” This case report describes a girl with familial adenomatous polyposis who exhibited heterosexual precocious puberty due to an adrenal tumor secreting cortisol and androgens; after her adrenalectomy, her hormone levels normalized and symptoms improved, illustrating the link between genetic syndromes and endocrine disorders.
33 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” This study found that finasteride treatment significantly reduced hirsutism scores in women with idiopathic hirsutism over 6 months and was well tolerated.
4 citations
,
December 2019 in “Minerva Urology and Nephrology” This study found that patients with non-muscle invasive bladder cancer who were treated with 5-alpha reductase inhibitors had lower recurrence rates and higher recurrence-free survival rates compared to untreated patients.
2 citations
,
June 2022 in “International Journal of Biomedicine” This article discusses the diagnosis and treatment options for hirsutism and reports no new clinical findings.
March 2023 in “Bagcılar medical bulletin” This case report highlights a rare diagnosis of an androgen-secreting adrenal tumor in a patient with hyperandrogenism and virilization symptoms, emphasizing the role of gynecologists in early detection.
17 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” This study found that finasteride may effectively reduce hirsutism in women with idiopathic hirsutism, as evidenced by lower Ferriman-Gallwey scores and hormone levels, without significant adverse effects.
5 citations
,
March 2016 in “CRC Press eBooks” This article explores the mechanisms of female hirsutism and highlights the effectiveness of eflornithine in reducing hair growth, with further removal requiring physical methods.
41 citations
,
December 2008 in “Current Opinion in Ophthalmology” This review describes techniques to manage intraoperative floppy iris syndrome linked to alpha-1 blocker use in cataract surgery, highlighting the need for patient disclosure of medication use but reports no new clinical results.
1 citations
,
July 2015 in “AACE clinical case reports” This case report details a postmenopausal woman with hyperandrogenism due to both adrenal adenoma and ovarian hyperthecosis, highlighting the effectiveness of hormonal suppression and venous sampling for diagnosis.
3 citations
,
January 1985 in “Acta Obstetricia Et Gynecologica Scandinavica” This case study describes a rare instance of a Granulosa‐Theca cell tumor causing sexual precocity in a 12-month-old infant, with significantly reduced estradiol levels following tumor removal.
6 citations
,
October 2010 in “Gynecological Endocrinology” This study found that relatives of women with symptoms of oligo-amenorrhoea and hirsutism experienced higher rates of hirsutism, menstrual disorders, infertility, childlessness, diabetes, and hypertension compared to relatives of symptomless women.
16 citations
,
January 2007 in “Archives of Iranian Medicine” In this study of premenopausal Iranian women with hirsutism, polycystic ovary syndrome was a common cause and frequently associated with menstrual irregularity, while elevated androgens or hyperandrogenic conditions were also observed.
January 2013 in “Revista Clínica Española” This review discusses female hyperandrogenism, detailing diagnostic criteria and treatment options without reporting new study results; it emphasizes improving health and quality of life for affected women.
1 citations
,
February 2017 in “Journal of gynecology and womens health” This review discusses the causes and management of hirsutism, recommending low-dose oral contraceptives with flutamide over cyproterone-containing preparations, but reports no new clinical findings.
47 citations
,
July 2016 in “Current pharmaceutical design” This review summarizes hair growth aspects, treatment options, and management strategies for hirsutism in women with polycystic ovary syndrome, without presenting new clinical findings.
October 1984 in “Kidney international” This case report describes a 23-year-old woman with a history of ambiguous genitalia and complex medical conditions, including a pelvic mass and hirsutism, observed from childhood to adulthood.
12 citations
,
January 2009 in “Gynecological Endocrinology” This case report identified ovarian hyperthecosis as the cause of recent-onset androgenic symptoms in a 73-year-old woman, which was confirmed by ovary removal and led to symptom improvement.
7 citations
,
January 2014 in “Case reports in endocrinology” This case report describes a testosterone- and cortisol-secreting adrenocortical oncocytoma causing hirsutism in a 23-year-old woman, highlighting adrenal oncocytomas as an important consideration for differential diagnosis.