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Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Eyelid cells share signaling components but differ in pathway activity.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Whale genes show changes that help them live in water, like less hair and better flippers.

FGF21 can help reduce skin inflammation caused by C. acnes.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Certain RNA molecules are important for the development of wool follicles in sheep.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.

Beta-caryophyllene, found in essential oils, helps wounds heal better in multiple ways.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Vitamin D is crucial for skin health and managing skin diseases.

Follicle Stimulating Hormone is important for fertility.

Skin heals with scars because only one type of fibroblast is used, not a mix.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.