Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, FCE 28260 showed greater potency than finasteride in inhibiting 5α-reductase enzymes and reducing prostate DHT levels in rats.

This compilation lists potential side effects, drug interactions, and trade names of various dermatological and antiretroviral medications, but it reports no original research findings.

This case report suggests a possible association between long-term finasteride use for male pattern baldness and the development of cataracts and intraoperative floppy-iris syndrome in a patient.

This study reports a case of a child with congenital skin fragility, alopecia, and cardiomyopathy due to compound heterozygous mutations in the DSP gene causing desmoplakin deficiency.

This study analyzed pexidartinib-associated adverse events from FDA data and reported common events such as hepatic issues and systemic reactions. It highlighted sex-specific susceptibilities and reinforced the need for risk mitigation and long-term monitoring in tenosynovial giant cell tumor management.

This study found that tildacerfont treatment in males with congenital adrenal hyperplasia reduced androgen levels and improved markers of testicular function, suggesting potential benefits for male reproductive health.

This pharmacovigilance study found strong disproportionality signals suggesting an association between finasteride and Peyronie's disease-related clinical features, but the evidence does not confirm a causal link.

This study highlights the successful design of recombinant fortilin constructs for potential drug development targeting atherosclerotic plaque formation in cardiovascular disease.

This study observed that using a 1064 nm Nd: YAG laser may stabilize hair loss and promote new growth in some females with frontal fibrosing alopecia, though individual results varied.

This study introduced a new in vivo angiogenesis assay using Gelfoam implanted in ND-GFP transgenic mice to efficiently identify angiogenesis stimulators and inhibitors through GFP visualization.

This study found that stressed dermal fibroblasts significantly increased dopa oxidase activity in melanocytes from hair, skin, and eyes, suggesting the involvement of fibroblast-derived factors like basic Fibroblast Growth Factor.

In this study, inactivating the TAF4 subunit of transcription factor TFIID in mouse epidermis disrupted gene expression linked to skin and hair function, and increased tumor risk.

In this case report, a 21-year-old woman's Fox-Fordyce disease was successfully controlled using topical 0.1% tretinoin cream.

This article discusses familial frontal fibrosing alopecia in two male families and reports no new clinical findings.

This study identified a large deletion in the desmoglein 4 gene as the genetic basis of the Iffa Credo "hairless" rat's skin phenotype, linking it to lanceolate hair mutations.

In these aquatic laboratory studies, researchers found that Finasteride reduced dihydrotestosterone levels in fathead minnows and increased gene expression related to androgen pathways in both minnows and medaka, indicating potential conservation of pharmaceutical effects on androgen biosynthesis across different species.

This study found that mackerel-derived fermented fish oil extract and its component DHA promote hair growth by activating anagen pathways in dermal papilla cells.

This study found that both finasteride and dutasteride significantly reduced L-DOPA-induced dyskinesia in a rat model of Parkinson's disease, with dutasteride showing greater effectiveness at lower doses.

This review discusses the increasing reports of frontal fibrosing alopecia, a form of scarring alopecia, and its potential link to autoimmune disorders, but reports no new clinical results.

This study found that finasteride induced infertility and increased endoplasmic reticulum stress in rats, but these effects were mitigated by DA-9401 administration.

This study reported no significant improvement in patients with frontal fibrosing alopecia treated with various therapeutic agents, highlighting the need for more evidence-based treatments, especially in those with active disease.

This study found that coactivating LIN28B and follistatin enhances cochlear supporting cells' ability to regenerate hair cells in neonatal mice by reprogramming them into progenitor-like cells.

This study analyzed data from the FDA Adverse Event Reporting System and found that finasteride had the highest reporting frequency and signal strength for drug-induced erectile dysfunction among 734 drugs, with compound preparations posing higher risks than single ingredients.

This pilot clinical study introduces DEC cells as a novel therapy for Duchenne muscular dystrophy, confirming safety and efficacy in seven patients up to 24 months post-treatment.

In this study, applying case-only trees and random forests to a prostate cancer prevention trial revealed genotypes that may influence the efficacy of finasteride for prostate cancer prevention.

This study suggests that linalool, a common allergen in personal care products, may contribute to frontal fibrosing alopecia pathogenesis by triggering immune responses and depleting hair follicle stem cells, especially in sensitized individuals.

This study found that follistatin and activin interactions are important for hair follicle development and cycling in mice, suggesting that they may regulate processes involving BMP-2 and its antagonist.

This study observed two cases of frontal fibrosing alopecia developing on preexisting vitiligo, suggesting a potential causal link between the two conditions.

This study found that the observed isotropic ss-ECD spectrum of finasteride is influenced by the anisotropy of locally oriented crystals, offering new possibilities for analyzing solid-state chiral materials.

In this study, FGF5-knockout Dorper sheep generated using CRISPR/Cas9 showed increased fine-wool and active hair-follicle density, suggesting potential therapeutic applications for androgen alopecia.