Frontal Fibrosing Alopecia in Association with Sjögren's Syndrome: More Than a Simple Coincidence

    October 2016 in “ Anais Brasileiros de Dermatologia ”
    Karina Furlan, Priscila Kakizaki, Juliana Cabral Nunes Chartuni, Neusa Yuriko Sakai Valente
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    TLDR Frontal Fibrosing Alopecia may be linked to autoimmune diseases like Sjögren's syndrome.
    The document described a case where a 50-year-old menopausal black female with Frontal Fibrosing Alopecia (FFA) also had Sjögren's syndrome (SS), suggesting a possible autoimmune link between FFA and autoimmune diseases. The patient, who had a 10-year history of symptoms associated with SS, such as dryness of the oral mucosa and eyes, showed progressive hair loss in the frontotemporal and eyebrow areas. Diagnosis was confirmed through clinical and histopathological examination. Treatment with intradermal triamcinolone, oral finasteride, chloroquine, and topical minoxidil over 4 years led to the stabilization of FFA but did not induce hair regrowth in the scarred regions. This case highlighted the need for screening for other autoimmune conditions in patients with FFA due to the implications for treatment and prognosis.
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