Fox-Fordyce Disease: Control with Tretinoin Cream

November 1979 in “ Archives of dermatology ”

R. Giacobetti

Fox-Fordyce disease tretinoin cream pruritic papular eruptions acanthosis keratotic plug Retin-A

TLDR Tretinoin cream successfully treated a woman's skin condition called Fox-Fordyce disease.

A 21-year-old woman with a three-year history of intensely pruritic papular eruptions in her pubic area and axillae, diagnosed with Fox-Fordyce disease, experienced successful control of her symptoms using topical 0.1% tretinoin cream. The condition, which worsened in warm environments and led to decreased hair growth in affected areas, showed histologic features consistent with Fox-Fordyce disease, including mild acanthosis and a keratotic plug.

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