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GlossaryKeratotic Plugs

small, hardened accumulations of keratin blocking hair follicles

Keratotic plugs, also known as keratin plugs or follicular plugs, are small, hardened accumulations of keratin and dead skin cells that block hair follicles. These plugs can lead to conditions like keratosis pilaris, where the skin becomes rough and bumpy, often resembling goosebumps. They are commonly found on the upper arms, thighs, and buttocks, and can sometimes cause inflammation or irritation.

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research Weathering of the Hairless Scalp: A Study Using Skin Capacitance Imaging and Ultraviolet Light-Enhanced Visualization

19 citations, July 2009 in “Clinical and Experimental Dermatology”

The study found that long-term sun exposure does not significantly affect follicular plugs on the scalp, and the scalp's appearance is unique compared to other body parts.

research Successful Management of Fox-Fordyce Disease in a 21-Year-Old Woman Using Topical 0.1% Tretinoin Cream

22 citations, November 1979 in “Archives of dermatology”

A woman with Fox-Fordyce disease had symptom relief using tretinoin cream.

research Chloracne: Histopathologic Findings in One Case

18 citations, April 2002 in “Journal of cutaneous pathology”

Tiny infundibular cysts are the main lesions in chloracne, not comedones.

research Dermoscopy of Discoid Lupus Erythematosus: Report of Two Cases

13 citations, July 2014 in “The Journal of Dermatology”

Dermoscopy helped diagnose discoid lupus erythematosus in two patients without needing skin biopsies.

research Fox-Fordyce Disease: Control with Tretinoin Cream

5 citations, November 1979 in “Archives of dermatology”

Tretinoin cream successfully treated a woman's skin condition called Fox-Fordyce disease.

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community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 1 year ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community Bryan Johnson just dropped his anti hair loss formula

in Treatment 339 upvotes 9 months ago

Bryan Johnson shared his hair loss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hair loss research.

community 22M Fin and min everyday for 10 months, looks like my right temple is still receding

in Finasteride/Dutasteride 67 upvotes 1 year ago

The user is seeking opinions on their hair loss, specifically the receding of their right temple. They are considering switching to Dutasteride but are unsure if it will help. Other users suggest that their hairline has improved with the use of Finasteride and Minoxidil. One user mentions using RU58841 to thicken their hairline.

community My skin is always dry and flakes like chalk (25)

in Transgender 6 upvotes 7 months ago

The user underwent a biopsy two years ago and was diagnosed with keratosis pilaris, leading to hair issues. They tried treatments including Minoxidil, betamethasone, lymecycline, topical Accutane, and dutasteride, as well as diet changes, without improvement in hair thickness or skin dryness.

community What are these spots on my scalp

in Treatment 51 upvotes 4 months ago

A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

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