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The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.

Researchers created human hair follicles using a new method that could help treat hair loss.

Special fiber materials boost the healing properties of certain stem cells.

New effective scar treatments are urgently needed due to the current options' limited success.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.

Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.