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Proper planning and technique in upper-face feminization surgery are crucial to avoid complications and revisions.

Facial feminization surgery is safe and patients are satisfied, but more detailed research is needed.

Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.

Facial contouring is crucial for the satisfaction and well-being of Chinese transgender females.

Facial feminization surgery helps make facial features more feminine, improving patient satisfaction and safety.

The document concludes that individualized Facial Feminization Surgery plans and comprehensive care are crucial for successful outcomes.

Dihydrotestosterone has a reduced effect on muscle-building in people with testicular feminization syndrome, especially after their gonads are removed.

Facial Feminization Surgery is effective and safe, with minimal complications.

The document recommends a multidisciplinary approach and experience sharing to advance facial feminization surgery as a medical field.

Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

The document concludes that facial feminization surgery improves psychological well-being and social acceptance for transgender individuals.

More research is needed to improve lower body gender affirmation techniques.

A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.

Significant facial gender transformation requires surgery, not nonsurgical methods.

Orthognathic surgeons play a key role in modifying masculine facial features to be more feminine, often improving transgender women's quality of life.

Forehead reduction and orbital contouring are important for satisfactory facial feminization in transgender females, with high satisfaction and low long-term problems.

A man's rare adrenal tumor caused feminization and white hair, was removed surgically, and improved after treatment.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Some men can have female pattern baldness without hormonal abnormalities or signs of feminization.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.